Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Question
Which of the following best describes the sequence variation within class | MHC molecules?
- A) Concentrated in the peptide-binding groove
- B) Concentrated near the transmembrane domain
- C) Concentrated within the cytoplasmic domain
- D) Concentrated within microglobulin
E) Distributed fairly evenly throughout the molecule
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- When an antigen complex is bound to a Class I MHC molecule, it can stimulate a A) B cell. B) plasma cell. C) helper T cell. D) cytotoxic T cell. E) Antigen presenting cell.arrow_forwardDescribe five important differences between class I and class II MHC proteinsarrow_forwardWhich of the following cells demonstrate MHC II molecules on their surface membrane? 1. B lymphocyte 2. macrophage 3. erythrocyte 4. neuron 5. smooth muscle cell Choose from the following: (A) 1 and 2 (B) 1, 2 and 3 (C) 1, 2, 4, and 5 (D) 1, 2, 3, 4, and 5arrow_forward
- Which type of MHC-class molecule is found on all nucleated cells and is used to communicate with cytotoxic T-lymphocytes? Which classes are displayed on APCs, and which class is used specifically to communicate with (a) helper T-lymphocytes and (b) cytotoxic T-lymphocytes?arrow_forwardThe function of the integrin can be described as follows:a). Media signal translation insideb). Stabilizes the binding of the TCR so that receivers are added and signals are sent insidec). Allows the receiver and its corrector to stick to the antigend). It helps the movement and development of lipid rafts that add and concentrate antigens together with TCRarrow_forwardDistinguish between class I and class II MHC proteins.arrow_forward
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