Which of the following are true statements regarding linkage disequilibrium? Please select all that apply. O Low recombination rate favors linkage disequilibrium. O Alleles at two loci are found together more frequently than could be explained by chance. Alleles don't have to be physically linked in order to be in linkage disequilibrium. Asexual reproduction is very effective at preventing linkage disequilibrium.

Researchers have discovered that some regions of chromosomes are more likely than others to cross over, these areas of frequent crossing over are called "recombination hot spots". Gene A and B are 500,000 bp apart - the genes are either side of a recombination hot spot. Gene C and D are also 500,000 bp apart but the region containing genes C and D are not near a recombination hot spot. Would the map distance between A and B be the same as the map distance between C and D? Explain your answer.

What is heterosis? Discuss whether it is caused by a single geneor several genes. Discuss the two major hypotheses proposedto explain heterosis. Which do you think is more likely to becorrect?

Which of the following statements are true regarding linkage? Select ALL that apply. When the map distance between two genes is less an 100 map units they are genetically linked When the map distance between two genes is less than 50 map units they are genetically linked genes on the same chromosome are always genetically linked. When two genes occur on the same chromosome they are physically linked When the map distance between two genes in less than 50 cM they are genetically linked.

The higher the recombination frequency (%), the more likely recombination will occur. The lower the frequency, the less likely recombination will occur. True or False

Describe how non-allelic recombination can change the genome Describe how recombination can result in loss of heterozygosity

Are two genes linked if not linked to the same marker on a chromosome.? Let's say we want to figure out whether two genes are linked on a particular chromosome so we cross-test them to a marker gene on that chromosome. Gene A is found to have an approximate 50% recombinant frequency so we say it's not linked to the marker. The other gene B however is found to have 40% recombinant frequency with our marker so we say it's linked. Now the question is are the two Genes A and B linked or not? Please explain your reasoning.

Genes A and B are 7.5 map units apart on one chromosome. Genes C and D are 8.0 map units apart on a second non-homologous chromosome. • The recombination frequency between A and B is? • The recombination frequency between A and C is? • The recombination frequency between C and D is? • The recombination frequency between B and D is?