Which of the following adapter proteins or protein pairs connects the actin filaments with the extracellular matrix? Ezrin Dystrophin/Dystroglycan complex Band 4.1/Glycophorin C Band 3/Ankyrin < Previous

When nerve cells contact each other, they form adherens junctions (AJs) at the point of contact. The main transmembrane (TM) protein in the junctions is N-cadherin. N-cadherin is a single pass TM protein with a short intracellular domain and a large extracellular domain on the amino end. Proper formation of the AJs requires both actin (MF) and microtubules (MTs). Motor proteins for MTs are dynein (-) end and kinesin (+) end (and were discovered by Michael Sheetz).  Maintenance of preformed AJs requires MFs . Adding drugs that disrupt MFs causes AJs to fall apart, and the N-cadherin is removed from the PM (by endocytosis). If the drugs are removed, MTs (& MFs) are required to restore the N-cadherin to the plasma membrane. choose answer for D1 and D2  D. Suppose cells contain a soluble kinase that modifies N-cadherin that has been removed from the PM. D-1. The kinase could catalyze modification(s) of the side chains of amino acids near (the N end) (the C end) (either end, but not…

You coat microfilaments with the myosin S1 fragment and add these coated microfilaments to the slide with Protein Y stuck on a slide. You observe the coated microfilaments move, and they move in the direction with the barbed ends leading. Your advisor is ecstatic with this observation, telling you that you have made a major discovery. What is novel about this discovery? ng. Microfilament movement Protein Y

Why is the proportion of actin within filaments in cells smaller than would be predicted by in vitro experiments?

The synaptosome-associated receptors referred to as v-SNARES are transmembrane proteins located on which of the following eukaryotic cell structures? mitochondrial membranes chloroplast membranes vesicle membranes lysosomal membranes peroxisomal membranes

The difference in microtubule bundles stabilized by Tau and MAP2 is due to differences in     amino acid sequences in the the tubulin subunits     whether or not the alpha subunit of tubulin is bound by GTP or GDP     the size difference between Tau and MAP2     the phosphorylation state of Tau and MAP2

What is a common feature of the voltage sensitive Ca++, Na+ and K+ ion channels? A single polypeptide sequence made up of 4 domains A voltage sensing S4 transmembrane domain A transmembrane S5-S6 hydrophobic subunit that binds the membrane A voltage sensing extracellular P loop

What key ATPase is important for maintaining this positive (outside) and negative (inside) transmembrane potential?

Identify how each of the following would pass through the plasma membrane: gases, large polar molecules, charged molecules (like ions), hydrophobic molecules, and small polar molecules. Be specific.

The following figure shows the 3D structure of a tubulin dimer. A mutation in the beta tubulin subunit (shown in red) prevents the binding of a GTP molecule. Predict the consequences that this mutation will have on the microtubule and on cell division. Please be specific. Alpha tubulin Beta tubulin