Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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- What would happen if you accidentally ingested a toxin that completely inhibited the function of the Ca2+ pumps in the sarcoplasmic reticulum membrane?
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All the membrane of the cells, as well as their organelle, possess several different types of ion channels and pumps. These help to regulate the concentration of the ions.
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- Please fill in the blanks: 21) the binding of ______________ to troponin removes troponin from ____________ on thin filaments to expose myosin binding sites 22) the energy released from the splitting of __________________ causes myosin cross bridges to pivot inward to pull the thin filaments inward toward the H zonearrow_forwardChoose the best description of how myosin and actin are arranged within the two types of protein filaments in myofibrils. a.) Actin makes up the think filaments, and myosin makes up the thin filaments. b.) Myosin makes up the think filaments, and actin makes up the thin filaments. c.) Myosin and actin are randomly interspersed in the think filaments but are absent from the thin filaments. d.) Myosin and actin overlap with each other to make up both the think and thin filaments.arrow_forwardWhich of the following regions of a sarcomere at rest is characterized by the presence of myosin only? a) A band b) H zone c) I band d) Z linearrow_forward
- In myogenesis, the assembling sarcomeres are integrated with the extracellular matrix (composed of collagen and laminin), across the plasma membrane (sarcolamina) by the following Integrin-vinculin complex Dystrophin glyco protein complex by actinin that bind collagen and filamin that bind actin filaments a and b a and c b and c none of thesearrow_forwardWhat event causes a troponin-tropomyosin complex to regain its original shape in muscle relaxation? a. stimulation of ACh receptors b. diffusion of Na+ back into transverse tubules c. return of Ca2+ into the sarcoplasmic reticulum d. breaking of the bond with tropomyosinarrow_forwardAcetylcholinesterase is an important molecule in the engine end plate to share: a) stimulates receptors in the postsynaptic membrane b) synthesizes acetylcholine from acetate and choline c) breaks down acetylcholine d) stimulates the release of Ca2 + from the sarcoplasmic reticulumarrow_forward
- The gap junction channel formed by connexin 43 in cardiac muscle has which of the following properties? OA. It links excitation and calcium release between the Sarcolemma and sarcoplasmic reticulum in skeletal muscle. OB. Is opened and closed by a gate on the intracellular side of S4 OC is composed of Hexamers. OD. Is opened and closed by positive charges on S4 OE. All of the abovearrow_forwardExplain what would happen if you skinned a muscle cell (removed the plasma membrane surrounding the cell), placed it in a saline bath containing ATP, and then added calcium to the bath.arrow_forwardCompare the rate of Ca2+ release from the sarcoplasmic reticulum to the rate of Ca2+ return back to the sarcoplasmic reticulum. Which of the following is true? The rate of ca2+ returns is faster than the rate of ca2+ release The rate of ca2+ release is faster than the rate of ca2+ return Rates of Ca2+ release from and return to the sarcoplasmic reticulum are the same.arrow_forward
- Which of the following labeled zones in the electron micrograph of the sarcomere shortens during contraction? OA) B) -E C) 00) D E) -C -8arrow_forwardTransmission of electrical signals in nerve and muscle cell is mediated by opening and closing of: 1) ion channels in the nuclear envelope 2) ion channels in the plasma membrane 3) the electron transport chain 4) the sodium potassium ATPase in the plasma membranearrow_forwardWhich of the following statements is unique to skeletal muscle? O a) skeletal muscle has striations O b) skeletal muscle is attached to bones O c) skeletal muscle is under voluntary control O d) skeletal muscle is multinucleated O all of the above O b, c, & d but not aarrow_forward
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