Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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What type of polymer is being formed in Reaction #3? Name an enzyme that can catalyze Reaction #3.

Is Reaction #3 favorable under mammalian cellular conditions when the concentration of dGTP is 0.2 M, dCMP is 20 mM, dGMP-dCMP is 7 mM, and PPi is 10 mM?  Use △G to support your answer. Show steps

Reaction #1 - AG° = 7.3 kcal/mol
GUANINE
OH
dGMP
Reaction #3
ofofofo
Reaction #2 - AG° = -12.2 kcal/mol
ofofa
OH
+
dGTP
GUANINE
OH
dGTP
GUANINE
CYTOSINE
OH
dCMP
OH
dCMP
GUANINE
OH
dGMP
CYTOSINE
0=4-0
GUANINE
CYTOSINE
OH
dGMP-dCMP
+ ofofo
PPi
GUANINE
CYTOSINE
OH
dGMP-dCMP
ofofo
PPi
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Transcribed Image Text:Reaction #1 - AG° = 7.3 kcal/mol GUANINE OH dGMP Reaction #3 ofofofo Reaction #2 - AG° = -12.2 kcal/mol ofofa OH + dGTP GUANINE OH dGTP GUANINE CYTOSINE OH dCMP OH dCMP GUANINE OH dGMP CYTOSINE 0=4-0 GUANINE CYTOSINE OH dGMP-dCMP + ofofo PPi GUANINE CYTOSINE OH dGMP-dCMP ofofo PPi
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