Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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**What is the lac operon?**

The lac operon is a set of genes in bacteria, particularly E. coli, that are involved in the metabolism of lactose. It is an example of an inducible operon that is activated in the presence of lactose and the absence of glucose. The operon includes three structural genes: lacZ, lacY, and lacA. These genes code for proteins needed to transport and break down lactose into glucose and galactose.

**Regulatory Mechanisms:**
- **Promoter:** The site where RNA polymerase binds to start transcription.
- **Operator:** A segment where a repressor binds, blocking RNA polymerase and preventing transcription.
- **Repressor:** A protein that inhibits the expression of the operon in the absence of lactose.
- **Inducer (allolactose):** A molecule that inactivates the repressor, allowing the operon to be transcribed when lactose is present.

The lac operon is a classical model of gene regulation, illustrating how cells can efficiently respond to environmental changes.
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Transcribed Image Text:**What is the lac operon?** The lac operon is a set of genes in bacteria, particularly E. coli, that are involved in the metabolism of lactose. It is an example of an inducible operon that is activated in the presence of lactose and the absence of glucose. The operon includes three structural genes: lacZ, lacY, and lacA. These genes code for proteins needed to transport and break down lactose into glucose and galactose. **Regulatory Mechanisms:** - **Promoter:** The site where RNA polymerase binds to start transcription. - **Operator:** A segment where a repressor binds, blocking RNA polymerase and preventing transcription. - **Repressor:** A protein that inhibits the expression of the operon in the absence of lactose. - **Inducer (allolactose):** A molecule that inactivates the repressor, allowing the operon to be transcribed when lactose is present. The lac operon is a classical model of gene regulation, illustrating how cells can efficiently respond to environmental changes.
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