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- Important characteristics of antimicrobial drugs include: a) readily delivered to the site of infection b) high toxicity against microbial cells c) do not cause serious side effects in humans d) remains active in body tissues and fluids e) all of the abovewhat is pharmacophore? what is the importance of pharmacophore in drug discovery?What are antimicrobial peptides?
- What are the characteristics of an ideal antimicrobial agent?Broad-spectrum drugs target a wide variety of bacterial pathogens. Even when the broad-spectrum drug is capable of killing a target pathogen, it may not be the best treatment. Which statement best explains why a broad spectrum drug might be an undesirable treatment choice? Broad-spectrum antimicrobials are usually toxic to the host cells. Broad-spectrum antimicrobials only work if they are used shortly after the infection begins. Broad-spectrum antimicrobials may kill much of the normal microbiota. Broad-spectrum antimicrobials are not able to kill bacteria that are in their log phase of growth. Broad-spectrum antimicrobials may stimulate excess growth of the normal microbiota.Name and describe three mechanisms of acquired antimicrobial resistance tools that microbes may use to thwart drug action.
- What is the connection between certain antimicrobial drugs and superinfections?What are the tests to determine the level of antimicrobial activity of a antimicrobial agent? How dilution susceptibility and disk diffusion test can be used to determine the effectiveness of a drug?What is DPI? What are the advantages of DPI over MDI? How drug is aerosolized from a DPI system? Please answer at your own words.
