What is AUC fc 0>12 hour rmulation (using the trar

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
Section: Chapter Questions
Problem 1SRQ
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Concentration (mg/L)
Time (hours)
Sustained-Release Tablet
Oral Solution
0.5
2.26
19.80
1
4.57
18.31
1.5
5.27
15.49
2
6.73
12.37
7.36
9.62
4
7.40
6.85
5
7.50
5.52
6.24
3.10
8.
4.70
1.79
12
2.76
1.58
Transcribed Image Text:Concentration (mg/L) Time (hours) Sustained-Release Tablet Oral Solution 0.5 2.26 19.80 1 4.57 18.31 1.5 5.27 15.49 2 6.73 12.37 7.36 9.62 4 7.40 6.85 5 7.50 5.52 6.24 3.10 8. 4.70 1.79 12 2.76 1.58
a. What is AUC 012 hour for the oral tablet
formulation (using the trapezoidal method)?
b. What is AUC 0 »12 hour
formulation (using the trapezoidal method)?
c. Which product has greater bioavailability?
for the oral solution
Transcribed Image Text:a. What is AUC 012 hour for the oral tablet formulation (using the trapezoidal method)? b. What is AUC 0 »12 hour formulation (using the trapezoidal method)? c. Which product has greater bioavailability? for the oral solution
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