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- How can you relate the two principles of Mendel to Chi-Square Values?Rough coat (R) is dominant over smooth coat (r) in guinea pigs, and black coat (B) is dominant over white (b). This pair of contrasting traits obeys both of Mendel’s laws. If a homozygous rough black is mated with a homozygous smooth white, give the appearance of each of the following: F1; F2; offspring of F1 mated with smooth, white parent; offspring of F1mated with rough, black parent.List four modified Mendelian ratios that you can think of.
- In a dihybrid cross of two bi-allelic Mendelian genes, A (two alleles – completely dominant A and recessive a), and B (two alleles – completely dominant B and recessive b), such that the parental generation comprises of pure-bred homozygotes (i.e. AABB with aabb), what are the expected genotype and phenotype ratios in the F1 and F2, if the F1 cross is (a) an intercross and if the F1 cross is (b) a testcrossGray seed color in peas is dominant to white. Assume that Mendel conducted a series of experiments where plants with gray seeds were crossed with each other and the following progeny were produced: 320 gray and 80 white. (a) What is the most probable genotype of each parent? (b) Based on your answer in (a) above, what genotypic and phenotypic ratios are expected in the progeny?What are the genotypes and phenotypes for Mendel’s true-breeding parent plants?
- What was the second filial (F2) generation in Mendel's experiment?On the basis of Mendel’s observations (i.e. Mendelian patterns), predict the results from the following crosses with peas. Show the results in terms of genotypes, phenotypes, and their proportions in the offspring. The progeny of a tall (dominant and homozygous) variety crossed with a dwarf variety. The progeny of (a) self-fertilized. The progeny from (a) crossed with the original tall parent. The progeny of (a) crossed with the original dwarf parent.According to Mendel’s second law, in the crossing between homozygous individuals concerning two pairs of nonlinked alleles, AABB x aaBB, what are the genotypical and phenotypical proportions in F1 and F2?
- Work out the Chi-Squared Goodness of Fit for Mendel's actual data on stem length: "Expt. 7: Length of stem. –– Out of 1,064 plants, in 787 cases the stem was long, and in 277 short. Hence a mutual ratio of 2.84:1. In this experiment the dwarfed plants were carefully lifted and transferred to a special bed. This precaution was necessary, as otherwise they would have perished through being overgrown by their tall relatives. Even in their quite young state they can be easily picked out by their compact growth and thick dark–green foliage." F2: O E O-E (O-E)^2 (O-E)^2/E # short 277 266 11 121 0.455 # tall 787 798 -11 121 0.152 sums: 1,064 1064 0.607 degrees of freedom = 2-1=1 Chi-squared value = .607 p-value: 0.25 < p < 0.50 Work out the Chi-Squared Goodness of Fit for Mendel's actual data on flower position: "Expt. 6: Position of flowers. –– Among 858 cases 651…Shown are F₂ results of a monohybrid cross performed by Mendel. a) Calculate the expected numbers of each type of pods. Full pods Constricted pods Total 882 298 1180 0.84 b) What do these p-values mean with regards to your null hypothesis? (Please choose either reject or fail to reject.)In which type of cross(es) can we apply and demonstrate the law of segregation and law of independent assortment? Why can’t we apply the 2 Mendelian laws on monohybrid crosses? Explain briefly. How can one use a pedigree chart to hypothesize how a certain condition is transmitted? Can a pedigree chart show probability of occurrence more accurately than the Punnett square? Why or why not?