What are tumor-specific transplantation antigens (TSTAS)?

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How does the epithelial-to-mesenchymal transition (EMT) contribute to tumorigenesis and disease progression?

Invasiveness occurs in tumours when they are looking to spread through the tissue of origin or to a distant site of metastasis. This process is often triggered or maintained by the tumour microenvironment. Critically discuss what the tumour microenvironment is and how it is proposed to aid in tumour migration.

In what ways can cancer be both a cause and a symptom ofimmunodeficiency?

A 42-year-old woman comes to the physician for a follow-up examination after two separate Pap smears have shown dysplastic epithelial cells. Results of a molecular diagnostic test show DNA that encodes high-risk versions of the human papillomavirus E6 and E7 proteins. The viral E6 protein binds to the cellular p53 tumor suppressor gene, causing it to be degraded. Which of the following best describes the mechanism by which the E6 protein causes cervical cancer? (A) Arrests the cell cycle (B) Enhances tissue invasion and metastasis (C) Inhibits telomerase expression (D) Prevents apoptosis (E) Sustains angiogenesis

How can the molecular analysis ofan individual tumor be more effectivelyused to design effective therapies tokill it?

What are the molecular mechanism of cancer development.  What mechanisms get mutated into oncovirus?

What is x-linked lymphoproliferative disease?

How do BRCA1 and BRCA2 function in regard to cell proliferation (are they proto-oncogenes, oncogenes, or tumor suppressor genes)?