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- In the nursing process of drug study of Heparin what will be the assessment,diagnosis,planning,intervention and evaluation?Name the commonly used anticoagulants for hematological studies. Give theirmechanism of action, specific uses, advantages and disadvantages.What is more preferred for drug therapy, conventional or modified release dosage forms? Please provide informations that would support the claim.
- How can you identify a rational prescription? Please shortly answer at your own easy words. Answer should be to the point.What is meant by a therapeutic window of a drug? b. Is it beneficial for a drug to have a wide or narrow therapeutic window? Motivate your answerWhat is Therapeutic Drug Monitoring (TDM) and under what circumstances would it be considered for a patient?
- a) Define EDso and TDso. Calculate the therapeutic index (TI) for each of the following drugs based on the dose-response curves provided. Comment on the safety of these two treatments. 100 80- 60- 40- 20- Drug 1 Therapeutic effect Toxic effect 100 200 300 400 500 600 700 Drug dose (mg) 100- Therapeutic effect 80- 60- 17 40- 20- 0- 10 20 Drug 2 40 Toxic effect 60 80 100 120 Drug dose (mg) 140Describe the significance of the use of pharmacokinetic parameters in case to calculate appropriate drug dosing regimens.Discuss three types of drug-drug interactions, and explain the links to pharmacodynamics and/or pharmacokinetics, with examples. Give the mechanims.