Using the AAV virus you created in the simulation, you introduce it to a mouse model for heart failure to determine the effect of SERCA2A in heart failure. a. Why would this virus only affect the myocardium and not other cell types within the mouse? b. Would the mouse then be able to spread that virus to other mice? Explain.

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Viral Replication

The virus is acellular and considered non-living outside the host cell. The replication of the virus occurs only inside the living cells. Only a few genes are present in the smallest virus, whereas many genes are present in the largest virus. These genes encode specific viral proteins.