Using acetylene as your only source of carbon atoms, identify a synthetic route for the production of 1-bromobutane. First, select the reagents necessary for the transformation shown, using no more than four steps in the synthesis. In part 2, you will synthesize any carbon reagents (other than acetylene) that were used in the synthesis. 2 H -H Br The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A B C MeONa NaNH2 t-BuOK D E EtBr H₂, Lindlar's cat. Br2, hv G H 1 HBr, ROOR H₂, Pt HBr
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
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