Aldehydes and ketones undergo acid-catalyzed reaction with alcohols to yield hemiacetals, compounds that have one alcohol-like oxygen and one ether-like oxygen bonded to the same carbon. Further reaction of a hemiacetal with alcohol then yields an acetal, a compound that has two ether-like oxygens bonded to the same carbon. Show the structure of the acetal that you would obtain by reaction of acetophenone with 2-propanol. • You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. Do not include lone pairs in your answer. They will not be considered in the grading. ?

Which of the following alcohols reacts fastest with HBr to give the corresponding alkyl bromide? 2-methyl-2-propanol O2-propanol methanol ethanol

When treated with base, the following compound undergoes an intramolecular aldol reaction and dehydration to give a product containing a ring. H Propose a structure for this product. base C4H6O + HO

To obtain 2,4,4-trimethyl-2-pentanal, write down the reaction mechanism using 2,2-dimethylpropanal and other necessary reagents.

Propose a mechanism for the acid-catalyzed reaction of cyclohexanone with ethylene glycol to give cyclohexanone ethylene acetal.

Propose a synthesis for the following compounds. As starting materials, you may use cyclopentanol, alcohols containing no more than four carbon atoms, and any reagents and solvents. Trans-cyclopentane-1,2-diol.

Would you expect 1-methyl-1-cyclohexanol to dehydrate at a faster or slower rate than cyclohexanol? Explain your answer by referring to the mechanism of the reaction. Explain step by step in details.

The product of reaction between formaldehyde with 2-methyl propanal give 2,2-dimethyl-3-hydroxy propanal 2,2-dimethyl-3-hydroxy propanone 2,2-dimethyl-3-hydroxy propanoic acid 2,2-dimethyl-3-hydroxy propanol 4-phenyl-3-buten-2-one prepared from reaction between Benzaldehyde with acetic acid Benzaldehyde with acetaldehyde Benzaldehyde with formaldehyde Benzaldehyde with acetone Which predict product for reaction between heptane-6-one-1-al with sodium hydroxide * 1-(2-hydroxycyclopentyl) pentanone 1-(2-hydroxycyclopentyl) butanone 1-(2-hydroxycyclopentyl) ethanone 1-(2-hydroxycyclopentyl) propanone