Answered: Uridine monophosphate (UMP) undergoes a…

Uridine monophosphate (UMP) undergoes a deuterium exchange in deuterated water as shown below. Propose a mechanism for this exchange.

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question

Uridine monophosphate (UMP) undergoes a deuterium exchange in deuterated water as shown
below. Propose a mechanism for this exchange. (

O
o-P-o-
6
OH
UMP
NH
D₂0
o-P-o-
D
OH
d-UMP
NH

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