Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Question

This is Fos-Jun dimer (1FOS). Is the leucine zipper at the C-terminus or at the N-terminus of the helices? Are the helices parallel or antiparallel? 

PDB ID 1FOS: Two Human C-Fos:c-Jun:dna Complexes
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Transcribed Image Text:PDB ID 1FOS: Two Human C-Fos:c-Jun:dna Complexes
Expert Solution
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Fos-jun family proteins are a class of proteins that belong to a large group of DNA binding proteins or transcription factors containing a highly conserved region that is responsible for the binding of DNA. These proteins form a leucine zipper in their structure with the repeating leucine residues present in the form of a dimer.

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