The Williamson ether synthesis involves treatment of a haloalkane with a metal alkoxide. Which of the following reactions will proceed to give the indicated ether in highest yield Reaction pair #1: CH3 CH3 CH;COK* CH3 (a) CI -OĊCH3 KCI + ĊH3 CH3 CH3 (b) -O'K* CH3CI OČCH3 KCI CH3 ČH3 Visited Reaction pair #2: CH3 CH3 (a) CH3CH2ČHO*K* CH;CH2CI CH3CH2CHOCH2CH3 KCI CH3 CH3 CH3CH2CHCI CH;CH2O'K* CH;CH2CHOCH,CH3 (b) KCI

Predict the product (including stereochemistry) when the following substance reacts under thermal conditions. H H3C- H3C- H.

Provide the products of the following reactions

23) Which reaction will yield the following alkene as only elimination product? NaOEt A) Br E-3- Br NaOCH, B) KOIBU "Br KHSOJAT D) 24) What is the product of the following transformation? AgOH Br A) B) OH C) D) OH 25) Rank the following alkenes according to their heat of combustion from the LOWEST to the HIGHEST. II II IV A) II < IV < I< III B) III < I< IV < || C)I< || < IV < IIl D) II < IV < |I < I

Q3. 2-Bromopentane, when treated with alcoholic KOH yields a mixture of three alkenes A, B and C. Identify A, B and C. Which is predominant?

+ H3C- CH₂ - CH2 - COR and have undergone McLafferty rearrangement and Ortho effect respectively. What are the possible fragments obtained as a result of these processes ? COOCH3 OH + (A) [R-CH₂-C (A) R-CH₂-CH₂ - CH₂ - COH @E OH]: [c C6H4 O and CO (B) H₂C=CROH and H₂C = CH₂ [2] : [ C₂H4O3 and CH4 (C) (D) H₂CCROH and C₂H4; [(C6H4O), CO and CH₂OH] RH, C₂H4 and CH₂CO; [(C₂H4O), CO and CH₂OH]

Give the major organic product(s) for the following reaction