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- Define fibronectinDescribe the importance of Ca++ and the difference between the sodium channels in the specialized endings and the voltage gated sodium channels in the sensory neuron.The concentration of potassium ions inside a nerve cell membrane is higher than the concentration of sodium ions outside the mem-brane, yet the inside of the membrane (where the cation concentra-tion is higher) is negative to the outside. Explain this observation in terms of permeability properties of the membrane.
- 2. a) sensation). the doctor decides to check the resting potential of her sensory nerves. The microelectrode is inserted and the intracellular potential is measured as -65 mv. What relative ionic concentrations are responsible for maintaining this membrane potential? A 47-year-old woman complains of paresthesis (tingling, pricking or burning a) [Na+ Jout > [Na+] in ; [K+]out > [K+]in b) [Na+ Jout > [Na+] in ; [K+]out [Ca2+]in d) [Na+ Jout [K+]in e) Active sodium potassium pumpQue:- Motoe lind plate diffee from neucon synape by all the followeng except:- nemon to a) Seconday ymaptic bleft . b) Toeminal button s myelinatid Presence f Aeynaptic Vesicles in teuminal beutton d) the neuroteane mittu is acetyl choline -Sensory receptor cells transduce physical or chemical stimuli: a) by limiting action potentials b) from chemical to electrical energy c) from an action potential into a synaptic potential d) by summing incoming action potentials e) into a change in the membrane potential of the sensory receptor cells
- Which of the conditions would result in the greatest action potential frequency in afferent neurons from muscle-spindle receptors?Which of the following is true regarding the difference between graded and action potentials? a.) Action potential occur only when the surface of the neuron is myelinated, but graded potentials occur in both in both myelinated and non-myelinated neurons. b.) The magnitude of action potential depends on the magnitude of the stimulus, whereas graded potentials are all or none. c.) The magnitude of graded potential depends on the magnitude of the stimulus, whereas action potentials are all or none.Discuss the importance of Sharpey’s fibers.
- Assume that two nerve fibers have the same diameter, but one ismyelinated and the other is unmyelinated. The conduction of anaction potential is most energy-efficient along which type of fiber?(Hint: Think about the required ATP.)a) Describe the behavior of an unaffected neuron sitting at its membrane resting potentialstimulated by a suprathreshold stimulus.b) Now, add the effects of the consumption of the Fugu toxin and stimulate that neuron with a supra-threshold stimulus.- Describe (and/or diagram) the effect on the membrane potential by supra-thresholdstimulation under this condition.c. Using any ONE (1) of the following three (3) means we have used to interpret the resultingmembrane potential for a neuron, describe the effect of the Fugu toxin on a neuron:i) Goldman’s equationii) “Driving” toward Ex of most permeable ioniii) Movement/flow of charge + chargesWhat are the three components of a typical somatic sensory neuron?