The pentose phosphate shunt is likely to be active when: a AMP levels are high b the organism has not had a meal for a long time. c an organism is growing d fatty acid beta-oxidation is active.
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The pentose phosphate shunt is likely to be active when:
| a |
AMP levels are high |
|
| b |
the organism has not had a meal for a long time. |
|
| c |
an organism is growing |
|
| d |
fatty acid beta-oxidation is active. |
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- Niacin is involved in the TCA cycle or ETC as:Which of the following will decrease the level of uric acid in the body? O Decrease optimal concentration of xanthine oxidase inhibitor O Lower deaminase action O Higher purine phosphorylase activityActivtion of a G protein can increase Calcium ion concentration in the cell and thus activate enzymes True O False
- Drugs that inhibit eicosanoids formation may be... * agents reducing substrate arachidonic acid availability agents inhibiting the cyclooxygenase or lipoxygenase enzymes or both agents blocking eicosanoid receptors. O all of themA defect in which of the following enzymes leads to Tay- Sachs disease? O Phospholipase CO a-galactosidase A O Hexosamidase A O SphingomyelinaseDigoxin, a toxin derived from the foxglove (shown), can be used to treat heart disorders such as atrial fibrillation. Digoxin's mechanism of action is to Inhibit the Na+/K+ ATPase. Which of the following is the most likely side effect of Digoxin treatment? Failure to transport glucose into cells during an extended fast O Failure to transport glucose into cells after after eating a large meal O Enhanced response of muscle cells to Acetylcholine O Failure to transport Cl" out of the cell using direct active transport
- All of the following are true with respect to alpha-glucosidase inhibitor, except:A. It inhibits intestinal alpha-glucosidase B. It decreases enzymatic conversion of oligo- to monosaccharidesC. It lowers postprandial glucoseD. It causes gastrointestinal disturbances.E. It may cause development of hypertension.Glutamine synthase has how many subunits? A、8 B、10 C、6 D、12explain how glucose breakdown, storage and synthesis occurs and how it is regulated in humans. Strictly no plagiarism.
- Which of the following is NOT produced during the oxidative phase of the pentose phosphate shunt? a Ribulose-5-Phosphate b Glyceraldehyde-3-phosphate c CO2 d NADPHYou have a crude lysate sample (CL) containing a mixture of six proteins (1, 2, 3, 4, 5, ẞ- galactosidase), and your goal is to obtain purified ẞ-gal. Some characteristics of these proteins are shown in the table below. Protein Alcohol dehydrogenase Carbonic anhydrase Insulin B chain Phosphorylase B Glutamic dehydrogenase B-galactosidase 45% Concentration of ammonium sulfate (AS) required for precipitation Molecular Weight (kDa) Isoelectric point (pl) 38 3.7 80% 65% 20% 30% 45% 28 4.8 4 5.3 98 6.8 49 9.5 115 5.3 You begin your purification by performing an ammonium sulfate (AS) precipitation. You add the appropriate concentration of AS to your CL sample, incubate overnight at 4°C, then centrifuge to generate a supernatant (AS-S) and pellet (AS-P). What concentration of AS will you use to precipitate Glutamic dehydrogenase? © 20% O 30% 45% 65% 80%Defects in enzymes can have serious metabolic consequences. The table below shows the profile of four different patients presenting with metabolite levels that differ from normal expected ranges Observed metabolic changes Select one: OOO PATIENT PROFILE W Elevated ammonia. Decreased oxidation of Increased liver fatty acids. glutamate. a. b. Patient X Patient WXD C. Patient Y O d. Patient Z PATIENT PROFILE X Increased ATP synthesis. 10 An investigation revealed one patient harboured mutations in the enzymes arginase and carnitine acyltransferase 2, negatively affecting each enzyme's function. Which patient can this be attributed to? 3 OND - === - PATIENT PROFILE Y D KOOKOOKOO Decreased lactate. PATIENT PROFILE Z Increased fatty acyl- CoA in mitochondria. Decreased glycolysis. Decreased 0 DOND oxaloacetate levels. 00 Report question issue ! No