Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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- Jeff's spermatogonium (precursor sperm cell before meiosis) looks like the cell on the left (only four chromosomes are shown. Assume all the other chromosomes behaved normally). After meiosis, Jeff makes a sperm that looks like the cell on the right. Assume the A/a and F/f genes are near the centromere where crossing over is suppressed. When did a nondisjunction event occur to create this sperm?arrow_forwardWhat kind of chromosomal mutations is/are produced by unequal crossing over?arrow_forwardA phenotypically abnormal individual has a phenotypically normalfather with an inversion on one copy of chromosome 7 and a phenotypicallynormal mother without any changes in chromosomestructure. The orders of genes along the two copies of chromosome7 in the father are as follows: R T D M centromere P U X Z C (normal chromosome 7)R T D U P centromere M X Z C (inverted chromosome 7) The phenotypically abnormal offspring has a chromosome 7 withthe following order of genes: R T D M centromere P U D T R Using a sketch, explain how this chromosome was formed. In youranswer, explain where the crossover occurred (i.e., between whichtwo genes).arrow_forward
- Two phenotypically unaffected parents produce two children withfamilial Down syndrome. With regard to chromosomes 14 and 21,what are the chromosomal compositions of the parents?arrow_forwardThe ABO blood type locus has been mapped on chromosome 9. A father who has type AB blood and a mother who has type O blood have a child with trisomy 9 and type A blood. Can you tell in which parent the non disjunction occurred? Explain.arrow_forwardIn the classic "X" figure of the chromosome, is the whole X from one parent, or is one side of the X from the mother and the other side from the father?arrow_forward
- In corn, the genes v (virescent seedlings), pr (red aleurone), and bm (brown midrib) are all on chromosome 5, but not necessarily in the order given. The cross: v+ pr bm/ v pr+ bm+ with v pr bm/ v pr bm produces 1000 progeny with the following phenotypes: v+ pr bm 226 v pr+ bm+ 229 v+ pr bm+ 153 v pr+ bm 185 v+ pr+ bm 59 v pr bm+ 71 v+ pr+ bm+ 36 v pr bm 41 What is the gene order, and the (b) genetic map of these three genes?arrow_forwardTwo phenotypically unaffected parents produce two children with familial Down syndrome. Regarding chromosome 14 and 21, what are the chromosomal composition of the parents?arrow_forwardA normal mother has translocations on chromosomes 14:21. With respect to chromosomes 14:21, how many combinations of chromosomes are possible? How many gametes are viable? If the woman has children with an normal father, what is the probability that there is a daughter with Down Syndrome or a son with an unaffected phenotype?arrow_forward
- When a single recombination event occurs between a normal chromosome and a chromosome with a paracentric inversion and within the inverted region, what are the expected meiotic products?arrow_forwardSET 2: In corn, the following allelic pairs have been identified in chromosome 3: +/b plant color booster vs. non-booster +/lg with ligule vs. without ligule +/v green plant vs. virescent A test cross between triple recessive plants and plants heterozygous for the three pairs gave the following progeny: + v lg 305 b + lg b v lg + + lg b v + 148 58 + + + 62 + y + 152 b + + 275 Total 1000 Calculate the parental and recombinant frequencies, the map distances between genes, and the coefficient of coincidence. Illustrate the gene map or sequence.arrow_forwardWhat is heterozygous variant?arrow_forward
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