The pedigree shows inheritance of an autosomal recessive disease in an extended family. Assume unrelated individuals marrying into the family do not carry the disease, unless there is reason to believe otherwise. What is the chance that IV-2 and IV-4 will have a child with the disease? Individuals I-1, Il-5, III-5 and Ill-16 have the disease. III-18 6 7 89 10 11 12 13 14 15 16 4 III-19 IV IV-3 IV-4 IV-5 IV-6 V-1 IV-2 a. 1/8 O b. 1/12 O c. 1/16 O d. 3/16 C e. 1/24 f. 1/32 g. 3/32 h. 1/64

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter11: Genome Alterations: Mutation And Epigenetics
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Problem 5QP: Achondroplasia is a rare dominant autosomal defect resulting in dwarfism. The unaffected brother of...
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Please help finding the chance. Correct answer is 1/32

身 三
P
The pedigree shows inheritance of an autosomal recessive disease in an extended family. Assume unrelated individuals marrying into the
family do not carry the disease, unless there is reason to believe otherwise.
What is the chance that IV-2 and IV-4 will have a child with the disease?
a
Individuals l-1, Il-5, IlI-5 and IlIl-16 have the disease.
21
3
II-18
5
7.
8.
9 10
11
12
13
14
15
16 17
III-19
IV
IV-3
IV-4
IV-5
IV-6
W-1
IV-2
a. 1/8
b. 1/12
C. 1/16
d. 3/16
e. 1/24
f. 1/32
g. 3/32
h. 1/64
11-21 PM
2.
Transcribed Image Text:身 三 P The pedigree shows inheritance of an autosomal recessive disease in an extended family. Assume unrelated individuals marrying into the family do not carry the disease, unless there is reason to believe otherwise. What is the chance that IV-2 and IV-4 will have a child with the disease? a Individuals l-1, Il-5, IlI-5 and IlIl-16 have the disease. 21 3 II-18 5 7. 8. 9 10 11 12 13 14 15 16 17 III-19 IV IV-3 IV-4 IV-5 IV-6 W-1 IV-2 a. 1/8 b. 1/12 C. 1/16 d. 3/16 e. 1/24 f. 1/32 g. 3/32 h. 1/64 11-21 PM 2.
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