The hydrolysis of carbobenzoxyglycyle-L- tryptophan catalyzed by the pancreatic carboxypeptidase was carried out according to the following equation. Carbobenzoxyglycyle- L- tryptophan + H20 - carbobenzoxyglycyine +L- tryptophar The data below represent the rate of formation of L- tryptophan at pH = 7.5 ,25°C. The results are listed as follows: 10.0 15.0 20.0 ISI (mM) Rate(mMs 2.5 5.0 0.024 0.036 0.053 0.060 0.064

Organic Chemistry
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Author:John E. McMurry
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Chapter21: Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions
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Problem 40MP: The hydrolysis of a biological thioester to the corresponding carboxyl-ate is often more complex...
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The hydrolysis of carbobenzoxyglycyle-L- tryptophan catalyzed by the
pancreatic carboxypeptidase was carried out according to the following
equation.
Carbobenzoxyglycyle- L- tryptophan + H20
→ carbobenzoxyglycyine +L- tryptophan
The data below represent the rate of formation of L
tryptophan at
pH = 7.5 ,25°C. The results are listed as follows:
20.0
IS] (mM)
2.5
5.0
10.0
15.0
Rate(mMs"
0.024
0.053
0.060
0.064
Transcribed Image Text:The hydrolysis of carbobenzoxyglycyle-L- tryptophan catalyzed by the pancreatic carboxypeptidase was carried out according to the following equation. Carbobenzoxyglycyle- L- tryptophan + H20 → carbobenzoxyglycyine +L- tryptophan The data below represent the rate of formation of L tryptophan at pH = 7.5 ,25°C. The results are listed as follows: 20.0 IS] (mM) 2.5 5.0 10.0 15.0 Rate(mMs" 0.024 0.053 0.060 0.064
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