The following molecule can be formed via an intramolecular aldol addition reaction. Draw the organic starting material needed to form the given B-hydroxycarbonyl compound. organic starting material B-hydroxycarbonyl NaOH ÓH

The following molecule can be formed via an intramolecular aldol addition reaction. Draw the organic starting material needed to form the given B-hydroxycarbonyl compound. organic starting material B-hydroxycarbonyl NaOH ÓH

EBK A SMALL SCALE APPROACH TO ORGANIC L

4th Edition

ISBN:9781305446021

Author:Lampman

Publisher:Lampman

Chapter22: 4-methylcyclohexene

Section: Chapter Questions

Problem 2Q

See similar textbooks

Related questions

Q: 3‑Methylbutanal undergoes an aldol reaction to form 3‑hydroxy‑2‑isopropyl‑5‑methylhexanal. Complete…

Q: Which one of these compounds would be the best starting material for a malonic ester synthesis? CH3…

Q: Draw the product for the following halogentation reaction: CH2=CH-CH2-CH3+Cl2 ––>

A: Halogenation is the addition of halogen to the compound.

Q: Draw the alkyl chloride for reaction 2. Reagents Ketone Product 1. Ethyl acetoacetate, NaOC2H5,…

A: Identify the alkyl halide that gives the following product.

Q: Synthesizing an Ether by a Two-Step Reaction Sequence Draw the product of the following two-step…

Q: What is the major product to the following elimination reaction? NaOH 'CI

Q: MgBr 1. (in THF) 2. H* (dilute) O the carbonyl oxygen is protonated first by an acid O the Grignard…

A: Grignard reagent react with carbonyl compound for new carbon-carbon bond .

Q: Which Grignard reagent, followed by aqueous workup, can be used to convert acetone into…

A: Ethyl magnesium bromide upon reaction with acetone followed by acidic workup gives…

Q: Draw the structure of the product of the following transformation. cat. TSOH H20

A: In this reaction, Acetal bond broken by acid water here acid is TsOH You can see mechanism and…

Q: Draw the major products formed in the following reaction involving an acid anhydride dissolved in…

A: The reaction of an acid anhydride with an alcohol gives ester and a carboxylic acid as the products.…

Q: Why is the Aldol reaction often called an Aldol condensation? O 1) The initially formed b-hydroxy…

A: The question is based on the concept of organic reactions. We have to identify the reason for…

Q: Draw the major product for the following reaction. 1. NaOH H20 + H. 2. Dil H+

Q: Draw the products for each intermediates listed to a Sweetener synthesis 1. 2-phenylethanal + NH3…

A: Since you have asked a question with multiple subparts, we will answer only first three subparts for…

Q: 1. NaOCH3 ? 2. H3O*

Q: Draw the enol form of the following ketone

A: First, let's discuss the enols. The enols are the type of reactive intermediate that has an alcohol…

Q: Draw the structure of the product formed when 2-methylbutanal is treated with cold aqueous base.…

Q: Draw the structure of each molecule. (a) 2,2-dimethylpropyl hex-3-ynoate; (b) cyanoethanoic…

A: (a) The structure for IUPAC name 2, 2-Dimethylpropyl hex-3-ynoate is:

Q: Draw the product formed when each dicarbonyl compound undergoes an intramolecular aldol reaction…

A: Given compounds,

Q: Click the "draw structure" button to launch the drawing utility. Draw the product formed when the…

A: Aldol condensation It is a condensation reaction where enolate ion reacts with a carbonyl to give…

Q: Name the following compound: O Butyl cyclohexanoate O Butanoic cyclohexanecarboxylic anhydride O…

A: The correct nomenclature of the above compound is given below

Q: Which Grignard reagent, followed by aqueous workup, can be used to convert acetone into…

Q: OH

A: The given compound is 2,5-dimethyl-2-hexen-3-ol. It is an enol system which undergoes enol-keto…

Q: Draw the major organic product formed when the benzoyl chloride undergoes a reaction with sodium…

Q: Aldol Condensation: Synthesis of 3-phenyl propenal

Q: Which Grignard reagent, followed by aqueous workup, can be used to convert acetone into…

Q: OH base + H20 heat H3C H. The aldol reaction is a carbonyl condensation reaction between two…

A: The beta-hydroxy aldehyde gives an E1cB elimination reaction to give an alkene. The first step of…

Q: During the metabolism of glucose, glyceraldehyde 3-phosphate is converted to dihydroxyacetone…

A: Please find below the stepwise mechanism for this reaction in the presence of acid

Q: 1. Which pair of aldehydes can lead to the following product? 10% NaOH(aq) ОН Н 2 moles of propanal…

A: Here the product formed is from aldol condensation reaction .

Q: H2 H3C° H3C, H2 H2O, H* .CH3 H2C CH3

Q: i) Synthons: Synthetic equivalents: ii) Synthons: OH Synthetic equivalents:

A: By disconnection , the fragment ions i.e. cation and anion are formed that may be real or imaginary…

Q: Draw the step-by-step mechanisms for the following reactions: a) Step 1 of the aldol condensation OH…

A: In an aldol condensation reaction product formed β- hydroxy carbonyl compound then elimination shows…

Q: Which of the following thiols will produce this disulfide after oxidation?…

Q: Which of the following choices is an intermediate A for the Claisen condensation reaction shown…

A: Here we are required to find the intermediate of the reaction .

Q: what product is formed after recrystallizing a mixture of 4-phenylcyclohexanone and…

A: Recrystallization of 4-phenylcyclohexanone and 4-phenylcyclohexanol forms a ketal .i.e.…

Q: A 4. What is the major product of the following intramolecular aldol condensation reaction? NaOH H20…

A: In this question we have to tell the product of the reaction.

Q: A key step in the synthesis of donepezil (trade name Aricept) is a directed aldol reaction that…

Q: Draw the product formed in each directed aldol reaction.

A: Aldol Condensation Reaction: The carbonyl compound having Alpha-hydrogen in the presence of base…

Q: Reaction with which of the following compounds in an acetylide reaction would lengthen the carbon…

A: Acetylide is a nucleophile formed by reaction of base on electron deficient species. Which on…

Q: Name a reaction in which a acetone reacts with NaOH to give alpha beta unsaturated ketone

Q: Draw the starting material that is required to prepare 1-phenyl-1-propanol using phenyl magnesium…

A: the starting material that is required to prepare 1 phenyl 1 propanol using phenyl magnesium…

Q: Be sure to answer all parts. Carry out the following synthesis from the given starting material. You…

A: Answer:- This question is answered by using the simple concept of chemical reaction of organic…

Q: The formyl of an aldose is converted to which functional group when oxidized? alkoxide…

Q: What is the general name for the reaction product formed in an aldol addition reaction? O y-Hydroxy…

A: Which one of the following is correct answer

Q: What hydrolysis products are formed when the following compound is treated with aqueous acid?

A: The hydrolysis products are formed when the given compound is treated with aqueous acid has to be…

Q: What type of intermediate us usually formed when an alkene reacts with a proton (H*)? An enol O A…

A: Alkene having sp2 hybridized. It react with proton (H+) to form carbocation.

Q: Draw reaction of an aldehyde or a ketone with cyanide ion under acidic conditions forms a…

A: Cyanohydrin Formation is a Nucleophilic Addition reaction. Aldehydes and ketones add reversibly to…

Q: How to Converting an OH Group into a Better Leaving Group?

A: Alcohols are the organic compounds which contains an -OH group. This group is not a good leaving…

Q: What aldol product is formed when two molecules of butanal react together in the presence of base?…

A: What aldol product is formed when two molecules of butanal react together in the presence of base?…

Concept explainers

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.

Question

The following molecule can be formed via an intramolecular aldol addition reaction. Draw the organic starting
material needed to form the given B-hydroxycarbonyl compound.
organic starting material
B-hydroxycarbonyl
NaOH
OH

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Step 3

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 3 steps with 1 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

What is the general name for the reaction product formed in an aldol addition reaction? O y-Hydroxy carbonyl compound a,B-Hydroxy carbonyl compound O a-Hydroxy carbonyl compound O B-Hydroxy carbonyl compound
Drawing an Enol and a Ketone Formed by Hydration of an Alkyne Draw the enol intermediate and the ketone product formed in the following reaction.
Draw the hemiacetal that is formed when the ketone is treated with one equivalent of methanol (CH,OH) in the presence of H₂SO OD C C OH X
Draw the hemiacetal and acetal formed when the carbonyl compound is treated with two equivalents of the given alcohol in the presence of H2SO4.
Draw the enol form of the following ketone
What is the product formed when each dicarbonyl compound undergoes an intramolecular aldol reaction, followed by dehydration.
Answer the following questions about curcumin, a yellow pigment isolated from turmeric, a tropical perennial in the ginger family and a principal ingredient in curry powder.a.In Chapter 11, we learned that most enols, compounds that contain a hydroxy group bonded to a C=C, are unstable and tautomerize to carbonyl groups. Draw the keto form of the enol of curcumin, and explain why the enol is more stable than many other enols. b.Explain why the enol O—H proton is more acidic than an alcohol O—H proton. c. Why is curcumin colored? d.Explain why curcumin is an antioxidant.
2 H3C H3C H C→XT OH H3C The aldol reaction is a carbonyl condensation reaction between two carbonyl partners and involves a combination of nucleophilic addition and a-substitution steps. One partner is converted into an enolate ion nucleophile and adds to the electrophilic carbonyl group of the second partner. In the classic aldol reaction, the carbonyl partners are aldehydes or ketones, although aldehydes are more reactive. The product is a ß-hydroxy carbonyl compound. base :0: OH H H Under reaction conditions slightly more vigorous than those employed for the aldol reaction, the ß-hydroxyl group is eliminated in an E1cB dehydration to give an a,ß-unsaturated carbonyl compound. Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instruct ns H3C heat OH H3C :0: H + H₂O H
Draw the product formed when phenylacetic acid (C6H5CH2COOH) istreated with following reagent. With some reagents, no reaction occurs. NaOH
Answer the following question about curcumin, a yellow pigmentisolated from turmeric, a tropical perennial in the ginger family and aprincipal ingredient in curry powder. Most enols, compounds that contain a hydroxy group bonded to a C=C, are unstable and tautomerize to carbonyl groups. Draw the keto form of the enol of curcumin, and explain why the enol is more stable than many other enols.
what product is formed after recrystallizing a mixture of 4-phenylcyclohexanone and 4-phenylcyclohexanol?
What products are formed when each acetal is hydrolyzed with aqueous acid?