The extravasation of neutrophils and lymphocytes occurs by generally similar mechanisms, although some differences distinguish the two processes. Which statements are true about lymphocyte extravasation? Naive lymphocytes are confined to the secondary lymphatic system by expression of the surface protein CD62L which recognizes HEV addressins. The adhesion step requires chemokine activation. Extravasation follows the order of chemoattraction, adhesion, rolling, and transmigration. Extravasation follows the order of rolling, activation, adhesion, and transmigration. The transmigration step requires chemokine activation. CCR7 is an essential chemokine receptor that guides lymphocyte extravasation into tissues during an immune response.

The extravasation of neutrophils and lymphocytes occurs by generally similar mechanisms, although some differences distinguish the two processes. Which statements are true about lymphocyte extravasation? Naive lymphocytes are confined to the secondary lymphatic system by expression of the surface protein CD62L which recognizes HEV addressins. The adhesion step requires chemokine activation. Extravasation follows the order of chemoattraction, adhesion, rolling, and transmigration. Extravasation follows the order of rolling, activation, adhesion, and transmigration. The transmigration step requires chemokine activation. CCR7 is an essential chemokine receptor that guides lymphocyte extravasation into tissues during an immune response.

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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