The cells from a person’s malignant tumor were subjected to insitu hybridization using a probe that recognizes a unique sequenceon chromosome 14. The probe was detected only once in each ofthe cells. Explain this result, and speculate on its significance withregard to the malignant characteristics of these cells.

Q: Expansion of a CAG repeat region by 1 repeat is an example of a frameshift mutation. Both DNA…

A: Frameshift mutation: It is a kind of genetic disorder that occurs due to insertion or deletion of…

Q: One way that researchers create a cell line that is "immortal" (divides forever in culture) is by…

A: Telomeres are repetitive sequences of DNA that are present at the ends of the chromosomes and help…

Q: explain the statement Duplications Provide Extra Gene CopiesThat Can Acquire New Functions

A: Genes are the basic biological unit of heredity. They are a segment of deoxyribonucleic acid (DNA)…

Q: In the treatment of cancer, the basis for many types of chemotherapyand radiation therapy is that…

A: The tumor is irregular growth of tissue. It is the first stage of tumor development. The…

Q: Where are DNase I hypersensitivity sites found, and what do they indicate about the nature of…

A: Deoxy ribonucleic acid (DNA) is the genetic material of most organisms that carry coded genetic…

Q: In Figure 5-12,a. Which Hfr gene enters the recipient last? (Whichdiagram shows it actually…

A: Some bacteria will have F-plasmid integrated with the chromosomal DNA, they are known as…

Q: In X chromosome inactivation...   A-Why it is inactivated? B- How it is inactivated? C-Is the…

A: Epigenetics is the subject of heritable differences in gene representation that do not require…

Q: What type of chromosomal rearrangement occurs o Breakage of two homologous chromosomes or sister…

A: A chromosomal rearrangement is a type of chromosome abnormality involving a change in the structure…

Q: 1.2 A colony of bacterial cells is exposed to UV-light. 1.2.1 What mutation will probably result…

A: MUTATION FROM UV LIGHT EXPOSURE Ultraviolet light induces specific mutations in the cellular and…

Q: Explain what happens to the sequence of DNA during trinucleotiderepeat expansion (TNRE). If someone…

A: Three nucleotide having a repeated sequence gets longer during trinucleotide repeat expansion (TNRE)…

Q: onsider the following segment of DNA, which is part of a linear chromosome: LEFT…

A: Answer.  Transcription is a process of the formation of transcript (RNA). It takes place by the…

Q: Why is the Philadelphia chromosome important to understanding & treating some cancers, especially…

A: Philadelphia chromosome is only present in the blood cells that are affected because of the damaged…

Q: A female fruit fly has one normal X chromosome and one X chromosomewith a deletion. The deletion…

A: Deletion: Chromosome segment comprises 1 or more genes separates and is lost. It is further of two…

Q: Cells exposed to ultraviolet light develop thymine dimersand visible light reverses this damage.…

A: Irradiation by the UV light causes pyrimidine dimers. The most common pyrimidine dimers formation is…

Q: Cells that continue toexpress telomerase include which cells?

A: A telomere is a region at the end of the eukaryotic chromosome that contains repetitive sequences.…

Q: Some germ-line mutations predispose individuals tocancer, yet often environmental factors…

A: A germline mutation is also called a germinal mutation. It refers to identifiable changes in the…

Q: All cells must replicate their DNA before each cell division. Why is it that DNA has to be…

A: Th deoxiribonucleic acid or the DNA is the genetic material in most of the organism

Q: IT has been shown that when a thin beam of light is aimedat a nucleus, the amount of light absorbed…

A: Heredity as we know is the passing on of traits from parents onto their offspring. Organisms that…

Q: A segment of cloned DNA containing a protein-encoding gene is radioactively labeled and used in an…

A: Cloning is a process in which the genetic characters is transferred from one organism to another via…

Q: Define about this- Cancer Cells Contain GeneticDefects Affecting Genomic Stability ?

A: Cancer is a condition when a few of the body's cells grow out of control and migrate to other bodily…

Q: What characteristic specifically defines a High Frequency Recombination (HFr) cell line?

A: plasmid is an extrachromosomal DNA that can replicate independently.  F plasmid is called fertility…

Q: Oncogenes sometimes result from genetic rearrangements(e.g., translocations) that produce gene…

A: The normal growth and functions of human cells are primarily based on the information stored in each…

Q: Hello, I did a Natural Transformation lab and have these questions to answer but don't really…

A: Natural transformation is a process by which some bacterial cells can take up and incorporate…

Q: Discuss the types of experimental observations that Mary Lyonbrought together in proposing her…

A: A sex chromosome also termed as allosomes are involved in the determination of sex in individuals.…

Q: Chromosome study requires visualization of metaphase chromosomes, how do we achieve this?

A: Chromosomes can be described as thread-like structures located inside the nucleus of animal and…

Q: Q: Hyperglycosylated genetically engineered proteins synthesized by some micro-organisms are usually…

A: DNA: Deoxyribonucleic acid (DNA) is a polymer made of two polynucleotide chains that coil around one…

Q: Describe two cellular mechanisms that can prevent mutationsfrom occurring.

A: Mutations are changes in the DNA sequence. Mistakes in DNA replication can result in mutations.…

Q: Read the statements below and determine which f the recombination mechanisms that it matches with -…

A: StatementTransformationConjugation (F+xF-)Conjugation (Hfr x F-)Generalized…

Q: E. coli cells usually have only one copy of the F plasmidper cell. You have isolated a cell in which…

A: Exchange of F plasmid or fertility factor occurs from F+ , a donor to F- , which acts as the…

Q: Which type of chromosomal abnormality—deletion,duplication, inversion, or translocation—would you…

A: Chromosomes are thread-like heritable structures that hold genetic information in the form of genes.…

Q: When the DNA of a human cell becomes damaged, the p53 geneis activated. What is the general function…

A: p53 gene: Tumor protein p53 gene also  p53 is a protein encoded by homologous genes in various…

Q: Describe how scientists use position effect variegationto study the mechanisms underlying the…

A: Position effect is described as the effect observed on the gene expression when there is a change in…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.