The cell cycle contains a series of events that control the division of cells. It is controlled by which of the following: P. dephosphorylation of cyclin-dependent kinases (S) Q. binding of CDK inhibitor proteins (R) R. cyclin synthesis and degradation (P) S. phosphorylation of cyclin-dependent kinases (Q) Q and R OP, Q, R, and S R and S P and Q

The cell cycle contains a series of events that control the division of cells. It is controlled by which of the following: P. dephosphorylation of cyclin-dependent kinases (S) Q. binding of CDK inhibitor proteins (R) R. cyclin synthesis and degradation (P) S. phosphorylation of cyclin-dependent kinases (Q) Q and R OP, Q, R, and S R and S P and Q

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Description: The cell cycle contains a series of events that control the division of cells. It is controlled by whichof the following:P. dephosphorylation of cyclin-dependent kinases (S)Q. binding of CDK inhibitor proteins (R)R. cyclin synthesis and degradation

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter5: Membranes And Transport

Section: Chapter Questions

Problem 1ITD: Some cancer cells are insensitive to typical chemotherapy. Research into the mechanisms underlying...

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The cell cycle contains a series of events that control the division of cells. It is controlled by which of the following: P. dephosphorylation of cyclin-dependent kinases (S) Q. binding of CDK inhibitor proteins (R) R. cyclin synthesis and degradation (P) S. phosphorylation of cyclin-dependent kinases (Q) R and S P, Q, R, and S Q and R P and Q
Which of the following would result in cell cycle arrest? O phosphorylation of Rb by G1-Cdk phosphorylation of p53 O phosphorylation of helicase by S-Cdk phosphorylation of M-Cdk by CAK phosphorylation of APC by M-Cdk
You are studying three proteins that you think are important Yor progression through the cell cycle. You know that one of them is a phosphatase (P1) and the other two are kinases ( K1 and K2). You add these enzymes in different combinations as shown below, and find that they have different effects on the activity of a cyclin dependent kinase, cdk2p. cdk2p Inactive Active cdk2p + K1 cdk2p + K2 Inactive cdk2p + K1 + K2 Inactive cdk2p + P1 cdk2p + P1 + K2 cdk2p + P1 + K1 Inactive Inactive Active cdk2p + P1 + K1 + K2 Active
In mammalian cells, different cyclin-CDK complexes regulate progression of cells through the cell cycle. Which of the following would be true during the cell cycle? Select all that apply Cyclin D phosphorylates and activates MCM protein, a helicase Cyclin B phosphorylates and breaks down the nuclear lamina OThe anaphase promoting complex, or APC/C is phosphorylated and activated by cyclin B Cyclin D helps promotes passage through the restriction point
(Q) During M-phase of cell cycle, active M-Cdk phosphorylates several target proteins in order to regulate their activities. Identify TWO specific examples of such target proteins that are phosphorylated by active M-Cdk, and explain how each of them affects the cell (i.e. their respective biological significance). i) target protein phosphorylated: _______________________________ Biological Significance: ii) target protein phosphorylated: _______________________________ Biological Significance:
Which of the following is false about cyclin-cdk complexes? OCdk's do not have to bind to cyclin proteins for complex to be active. OCdk/cyclin complexes phosphorylates proteins required to trigger next cell cycle phase. Process acts as molecular brakes to ensure cell is ready to continue with cell cycle. O Cyclin concentrations increase gradually, but cdk must be phosphorylated by specific kinase for complex to be active
1. (a) Describe the generalized model of the cell cycle. Demonstrate how cyclins and cyclin-dependent kinases can regulate the cell cycle. (b). Describe three ways in which cells lose their ability to regulate their growth to become cancerous.
After DNA damage (e.g. caused by X-ray exposure) in eukaryotic cells, the cell cycle can be arrested by the stabilisation of the protein which drives the transcription of the gene, whose protein product interacts with the G1/S-Cdk and S-Cdk complexes. O PDGF, acetyltransferase O phenylalanine hydraxylase, PDGF O p53, acetyltransferase O p53, p21 O p21. p53
(46) A mutated form of protein p5x is found in patients with squamous cell carcinoma. In vitro studies show that the normal p5x molecule binds to DNA, and neoplastic cells accumulate in the G0 phase of the cell cycle. In contrast, the mutated form of p5x does not bin d to DNA. These finding are most characteristics of which of the following? (A) Growht factor receptors (B) GTP-binding protein (C) Nonreceptor tyrosine kinases (D) Oncogene proteins (E) Tumor suppressor gene proteins
Describe kinases and cyclins. How do they interact to cause cells to move through the cell cycle?
(a) the cell cycle is divided into different phases (referred to as M, G0, G1, S and G2); Can you account for what happens during the different parts of the cycle and out of it is checked? ( b) What is the difference between apoptosis and necrosis? ( c) What are caspases and what is their function in the cell?
Which of the following statements is a lie?Select one: a. If damaged DNA is detected during the cell cycle, negative regulation is responsible in stopping the cell cycle. b. There are four cyclin proteins involved in the positive regulation of the cell cycle and they have fluctuating levels. c. To activate cyclin-dependent kinases (Cdks), they must bind to another kinase.