The BP requires ephedrine (C10H15NO·½H2O) to contain not less than 99.0 per cent and not morethan 101.0 per cent C10H15NO with respect to the anhydrous substance. Use the data below tosee if the sample complies with this requirement.(a) Loss on drying: 0.3152 g of sample had a mass of 0.2991 g after drying.(b) Assay: 0.3751 g was dissolved in ethanol and 25.0 mL of 0.0935 M hydrochloric acidadded. The excess acid was back titrated with approximately 0.1 M sodium hydroxide and1.93 mL was required. A blank titration was performed and required 24.17 mL of thesodium hydroxide.

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The BP requires ephedrine (C10H15NO·½H2O) to contain not less than 99.0 per cent and not more
than 101.0 per cent C10H15NO with respect to the anhydrous substance. Use the data below to
see if the sample complies with this requirement.
(a) Loss on drying: 0.3152 g of sample had a mass of 0.2991 g after drying.
(b) Assay: 0.3751 g was dissolved in ethanol and 25.0 mL of 0.0935 M hydrochloric acid
added. The excess acid was back titrated with approximately 0.1 M sodium hydroxide and
1.93 mL was required. A blank titration was performed and required 24.17 mL of the
sodium hydroxide.

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