The AMPA receptor is a and the NMDA receptor is a, a. transmitter-gated ion channel, transmitter-gated ion channel b. transmitter-gated ion channel, metabotropic receptor c. g-protein-coupled receptor, transmitter-gated ion channel d. g-protein-coupled receptor, metabotropic receptor e. metabotropic receptor, transmitter-gated ion channel
AMPA receptors:- AMPA (α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate) receptors are a type of glutamate receptor responsible for mediating the fast, synaptic transmission in the central nervous system. The AMPA receptor consists of four subunits, GluA1-4. Furthermore, the GluA2 subunit is not permeable to calcium ions since it contains arginine in the TMII region. (GluA2(R)) form. Besides, AMPA receptors are involved in the transmission of the bulk of the fast, excitatory synaptic signals. The intensity of the post-synaptic response depends on the number of receptors at the post-synaptic surface. The type of agonist which activates the AMPA receptors is α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid. Moreover, the activation of the AMPA receptor results in the nonselective transport of cations like sodium and potassium ions into the cell. And, this generates an action potential in the post-synaptic membrane.
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