The 5′ region of the TPP riboswitch in Bacillus subtilis is very similar to the TPP riboswitch in E. coli. Even so, the riboswitch in B. subtilis regulates transcription, whereas the one in E. coli regulates translation. What is the role of the 5′ region in both riboswitches? How can one riboswitch regulate transcription while the other regulates translation?

Human Anatomy & Physiology (11th Edition)
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The 5′ region of the TPP riboswitch in Bacillus subtilis is very similar to the TPP riboswitch in E. coli. Even so, the riboswitch in B. subtilis regulates transcription, whereas the one in E. coli regulates translation. What is the role of the 5′ region in both riboswitches? How can one riboswitch regulate transcription while the other regulates translation?

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Step 1

Bacterias are genetically regulated by RNA, they use a ribonucleic acid sequence encoded within mRNA that directly influences the expression of genes encoded in the full transcript called a cis-acting element. Riboswitches are the regulatory mRNA elements that bind metabolites or metal ions as ligands and regulate mRNA structure by the production of alternative structures in response to ligand binding.

Step 2

Bacterias are genetically regulated by RNA, they use a ribonucleic acid sequence encoded within mRNA that directly influences the expression of genes encoded in the full transcript called a cis-acting element. Riboswitches are the regulatory mRNA elements that bind metabolites or metal ions as ligands and regulate mRNA structure by the production of alternative structures in response to ligand binding.

 

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