Tautomerization: A. Causes frameshift insertions B. Causes frameshift deletions C. Results in permanent chemical changes in nitrogenous bases D. Cause transition mutations E. Cause transversion mutations
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- Exposure to various chemicals can cause DNA mutations. Classify the examples as representative of transition, transversion, or nsertion/deletion mutations. Transition replacement of T:A: with C:G treatment with nitrogen mustard causes this type of mutation oxidative deamination via nitrous acid causes this type of mutation treatment with 5-bromouracil causes the replacement of A:T with G:C Transversion replacement of G:C with T:A Answer Bank Insertion/Deletion the removal of one or more base pairs treatment with proflavin causes this type of mutation. Discuss how Benzer used deletions to map mutations inthe rII regionIdentify the best match between the mutation description and term. a. Transversion: results in a change in single nucleotide from a purine to another purine or a pyrimidine to another pyrimidine b. Nonsense mutation: a change in the DNA that changes the codon code from one amino acid to another amino acid c. Missense mutation: causes a drastic change in phenotype because the change causes a premature stop in the amino acid sequence d. Indel: has the potential to cause large changes in transcription and subsequence amino acid sequence due to reading frameshifts
- Choose from : insertion with frameshit, deletion with frameshift, silent mutation, deletion without frameshift, missense mutation, insertion without frameshift, nonsense mutation The wildtype sequence of a gene is the following: wt: 3' TAC AAA TCT AGC CCG 5' and the following 3 mutations were found:, indicate what type of mutation this is 1: 3' TAC AAA TCA AGC CCG 5' ; 2. 3' TAC AAA TCT ATC CCG 5'. ; 3. 3' TAC AAA AGC CCG 5'. ;an adult with a history of tanning has his genome sequenced. The beginning of a protein coding region of his DNA reads ATGGGGATATGGCAT. If the protein coding region of a healthy adult reads ATGGGGATATGAGCAT identify the site and type of mutation. What might happen because of this mutationDirection: On the worksheet, all the DNA sequences run from 3' to 5'. Supply the corresponding amino acid base on the DNA sequence provided per item. Determine the type of mutation and explain its effect on the expression of amino acids. 1. DNA Sequence: TAC TCC GGC TCT CCC AGT TGA ACT inim Mutated Sequence: TAC TCG GCT CTC CCA GTT GAA CT Original Amino acid: Mutated Amino Acid: What mutation have occurred in the sequence? How does it affect the expression of amino acids? 2. DNA Sequence: TAC TCC GGC TCT CCC AGT TGA ACT Mutated Sequence: TAC TCT GGC TCT CCA AGT TGA ACT ww mm Original Amino acid: Mutated Amino Acid: What mutation has occurred in the sequence? How does it affect the expression of amino acids?
- Mutation rates vary for genes. All of the following are factors that influence the mutation rate of a gene EXCEPT: O repetitive nucleotide sequences size of the gene spontaneous chemical changes: C/G base pairs are more likely to mutate than A/T pairs O all of these factors influence gene mutation rates exposure to environmental triggersWhat type of mutation is shown below: CGG GGG GAG TCT TTT TAT GCA GCT changes to: CGG GGG GAG CTT TTTATG CAG CT A frame shift mutatuion which resulted from a deletion. O Point mutation in which one nucleotide was changed. O Point mutation in which a length of nucleotides were changed. O A frame shift mutatuion which resulted from an insertion.Explain why point mutations may be silent, but frameshift mutations rarely are.
- Induced mutation are characterized by: Select the correct response: Exposure to free radicals that has been deposited in the aqueous phase and diffuses towards the cell that is followed by the inhibition of its replication or transcription, or may cause deletion. Physical and chemical agents that results in the transition, transversion, and framshift mutations of bases and other structural units that affects the overall function of a nucleic acid. Physical and chemical agents that results in the alteration of the electoronic characteristics of the bases and other structural units that affects the overall function of a nucleic acid. Point mutations that results in the transition, transversion, and framshift mutations of bases and other structural units that affects the overall function of a nucleic acid. Physical and chemical agents that results in the alteration base pairing where tautomers are formed affects the overall function of a nucleic acid.Explain the difference between a gain-of-functionmutation and a dominant-negative mutation. Why areboth these types of mutation usually dominant?What are deletion mutations? Also plzz mention its types Quickkkkk