Synthesis. Developments in medicine follows advances in synthetic chemistry. Anyone that disagrees would perhaps be well served to imagine the state of surgery if organic chemists had not developed local anesthetics. The following structure is the free base of hexylcaine (1), a local anesthetic developed by Merck. Propose a synthesis of 1 starting from benzene and acyclic components containing five carbons or less. Justify any chemo-, regio- or stereo selective steps in your synthesis. ( (1)

Synthesis. Developments in medicine follows advances in synthetic chemistry. Anyone that disagrees would perhaps be well served to imagine the state of surgery if organic chemists had not developed local anesthetics. The following structure is the free base of hexylcaine (1), a local anesthetic developed by Merck. Propose a synthesis of 1 starting from benzene and acyclic components containing five carbons or less. Justify any chemo-, regio- or stereo selective steps in your synthesis. ( (1)

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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