Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Suppose calcium ion is maintained within an organelle at a concentration1000 times greater than outside the organelle (T = 37 °C). Assuming the membrane is permeable to Ca2+, what is the contribution of Ca2+ to the membrane potential? Which side of the organelle membrane is positive, and which is negative?
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- In the Nernst equation [V = 62 log10 (Co / Ci)], the term Co represents: cell bio the intracellular concentration of calcium the extracellular concentration of potassium the extracellular concentration of sodium the intracellular concentration of potassium the membrane potential (in millivolts)arrow_forwardYour friend has made an artificial membrane to study ion concentration gradients in a laboratory and is confused after observing the ion concentration gradient in the image below. Initially (Time 1) there was a very strong concentration gradient across the membrane and your friend expected that ions would move until the concentrations were equal across the membrane. For a short time there was movement of ions but this soon stopped and there is no further change in the situation no matter how long you wait (see Time 2). Time 1 You friend is confused because there is still a strong concentration gradient and there are open ion channels available. So why don't the concentrations equalise? After thinking about it you realise that there must be some information that is incorrect or missing from the diagram above. Select the image below that explains why the ion concentrations remain unequal across the membrane Time 2 Select the correct image by clicking on it (you can only select one…arrow_forwardThe cytoplasm of a certain cell is composed of a solution that is 98% water, 2% solutes. Consider the solution shown in the beaker in this picture: FOOE OOS Foor solution. [Select] Cytoplasm is 98% water, 2% solutes. The solution in the beaker would be considered when compared to [Select] The plasma membrane is impermeable to solutes. Beaker solution is 98% water, 2% solutes the cell. We would expect that the cell would [Select] if it was placed in the would account for whatever changes might occur to the volume of the cytoplasm of the cell when it is placed in the solution.arrow_forward
- How is the cell membrane like a battery? Membrane potential (think of the properties of a battery) Resting membrane potential Na+ and K+ ions -> -70 mV Na+/K+ pump Stored energy for workarrow_forwardThe salt concentration in the cytosol of body cells of seawater fish is lower than it is in their environment. This causes the fish to continually lose water. To compensate for this loss, seawater fish continuously ingest water and rely on membrane-bound proteins on their gills for the removal of salt ions back to the environment. Which of the following describes the most likely mechanism of membrane transport used by seawater fish to remove the salt ions? A B с D exocytosis simple diffusion active transport facilitated diffusionarrow_forwardIn the situations described below, what is the free energy change if 1 mole of Na+ is transported across a membrane from a region where the concentration is 48 μM to a region where it is 110 mM? (Assume T=37∘C.) When the transport is opposed by a membrane potential of 70 mV.arrow_forward
- Suppose that a plant cell membrane is permeable with Na*, CI ions and H20, but not with proteins. In addition, it is assumed that 0.05 M Nacl aqueous solution is present outside the cell membrane, and 0.001 M of protein (P) is present inside. The protein is ionized to p, z = 20, and the opposite ion is CI". From this, calculate the theft potential that occurs between the cell membrane and the external solution in equilibrium. Assume that the activity coefficient of all ions is 1.0.arrow_forwardwhat would the membrane potential be if the membrane became 10X more permeable to both sodium and chloridearrow_forwardAmong membrane transport processes below, which one does NOT require ATP energy?arrow_forward
- The equilibrium potential for a given ion (Eion) is a theoretical value. For a given concentration gradient of an ion, the equilibrium potential is the charge inside the cell required to hold an ion at that concentration. That is, it is the charge required to perfectly oppose the drive of the ion to move down its concentration gradient. So, if the concentration of Nat is higher outside the cell than inside, its equilibrium potential (ENa) must be I and if we add more sodium to the extracellular fluid, then ENa will II.arrow_forwardIdentify how each of the following would pass through the plasma membrane: gases, large polar molecules, charged molecules (like ions), hydrophobic molecules, and small polar molecules. Be specific.arrow_forwardIN the figure for D: The organization of a protein that normally resides in the plasma membrane in shown in the figure below. The boxes labeled 1,2 3 and 4 represent membrane-spanning sequences and the arrow represents a site of action of signal peptidase. Given this diagram, which of the following statements must be true? (C) (D) oplasmic Reticulum The N-terminus of this protein is in the ER lumen The mature version of this protein will span the membrane twice, with both the N- and C-terminus in the cytoplasm. Two of the answers are correct The C-terminus of this protein is in the ER lumenarrow_forward
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