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Starting with acetoacetic ester and any other reagents propose a synthesis and a mechanism for the following compound:

Starting with acetoacetic ester and any other reagents propose a synthesis and a mechanism for the following compound:

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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### Organic Chemistry Problem: #### Problem 6: Starting with acetoacetic ester and any other reagents, propose a synthesis and a mechanism for the following compound: #### Structure: The compound is a three-ring structure with a central five-membered ring. The five-membered ring consists of two nitrogen atoms adjacent to each other (positions 1 and 2) and a carbonyl group (C=O) at position 4. Attached to position 3 is a cyclopropyl group (a three-membered carbon ring). Hydrogen atoms are attached to positions 1 and 2 nitrogen atoms, and a methyl group (CH3) is attached to the carbon at position 4. 1. **Explanation of the Structure**: - The compound features a central five-membered ring with the molecular formula C5H6N2O. - Positions of atoms: - Nitrogen atoms at positions 1 (N-H) and 2 (N-H). - Carbonyl group (C=O) at position 4, along with a methyl group (CH3) on the adjacent carbon. - Cyclopropyl group attached to the ring. #### Graphical Illustration: There is one graphical structure in the problem which is a chemical structure of the target compound. Below is an explanation of the relevant structure components: 1. **Five-membered ring**: - Two nitrogen atoms (N-H) at adjacent positions. - Carbonyl group (C=O) at position 4. - Methyl group (CH3) attached to the carbon at position 4. - Cyclopropyl group (three-membered carbon ring) attached at position 3. Understanding this problem involves proposing a synthesis mechanism starting from acetoacetic ester and analyzing the potential reagents and steps to form the described structure.
Transcribed Image Text:### Organic Chemistry Problem: #### Problem 6: Starting with acetoacetic ester and any other reagents, propose a synthesis and a mechanism for the following compound: #### Structure: The compound is a three-ring structure with a central five-membered ring. The five-membered ring consists of two nitrogen atoms adjacent to each other (positions 1 and 2) and a carbonyl group (C=O) at position 4. Attached to position 3 is a cyclopropyl group (a three-membered carbon ring). Hydrogen atoms are attached to positions 1 and 2 nitrogen atoms, and a methyl group (CH3) is attached to the carbon at position 4. 1. **Explanation of the Structure**: - The compound features a central five-membered ring with the molecular formula C5H6N2O. - Positions of atoms: - Nitrogen atoms at positions 1 (N-H) and 2 (N-H). - Carbonyl group (C=O) at position 4, along with a methyl group (CH3) on the adjacent carbon. - Cyclopropyl group attached to the ring. #### Graphical Illustration: There is one graphical structure in the problem which is a chemical structure of the target compound. Below is an explanation of the relevant structure components: 1. **Five-membered ring**: - Two nitrogen atoms (N-H) at adjacent positions. - Carbonyl group (C=O) at position 4. - Methyl group (CH3) attached to the carbon at position 4. - Cyclopropyl group (three-membered carbon ring) attached at position 3. Understanding this problem involves proposing a synthesis mechanism starting from acetoacetic ester and analyzing the potential reagents and steps to form the described structure.
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