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We know that short term habituation is due to changes in the presynaptic sensory neuron. What possible changes could explain the results of Kandel’s experiment? Which possibility currently has the most experimental support?
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- 7. You stimulate a presynaptic cell and record from the postsynaptic neuron of each pair. For each mutation below, describe the following: i) After the first stimulus, how does the excitatory postsynaptic potential (EPSP) you record from the postsynaptic neuron differ from the EPSP recorded from a wild-type animal? Does it increase, decrease, stay comparatively the same, or fail to be generated at all? ii) After five stimulations of the presynaptic cell in quick succession, how does the EPSP you record from the mutant animal differ from that in the same experiment on a wild-type animal? Explain your reasoning in each case. The mutations are as follows: 7A. Mutation of the voltage-gated Ca2+ channels of the presynaptic terminal. The mutant channels have a lower opening threshold.3) Where is TTX obtained from? 4) What was the effect of Lidocaine? 5) Relate 4 above to Lidocaine's clinical use Activity 5: Measuring Refractory Periods of Neurons: this simulation you will gradually decrease the time between successive stimuli until: d. A stronger stimulus is required to generate a 2nd AP (relative refractory period) of b. A second AP cannot be produced at all (absolute refractory period). Use your data from Chart 5 to answer the questions below: 1) What interval between stimuli initially prevented a second AP? 2) Was this the relative or absolute refractory period? 3) What was the minimum interval for relative refractory period (hint: minimum interval where you could still generate a second AP with a stronger stimulus? 4) What interval completely prevented a second AP? 5) Is this relative or absolute RP? ME Activity 6: The "Language" of the nervous system: Frequency of Aps. Use your data from Chart 6 to answer the questions below: 1) What is the effect of…What happened when Thompson temporarily inactivated the lateral interpositus nucleus of a rabbit’s cerebellum during learning? a. The rabbit showed no responses during training but showed evidence of learning as soon as the lateral interpositus nucleus recovered. b. The rabbit showed no responses during training, and after the lateral interpositus nucleus recovered, the rabbit learned at the same pace as a rabbit with no previous training. c. The rabbit showed no evidence of learning during training and no ability to learn even after the lateral interpositus nucleus recovered. d. The rabbit showed normal responses during training but forgot them after the lateral interpositus nucleus recovered.
- A mutation causes a switch in dopamine receptor G-protein-coupled mechanisms in the basal ganglia, causing D1 and D2 receptors to swap their G-protein subunits. If these animals began showing Parkinson-like neuronal degeneration, what would be the resulting motor function? Question 1 options: A) Hyperkinetic B) No change C) HypokineticDiscuss the early and late associative effects in the cellular processes of neurons that occur as a consequence of classical conditioning.Using microelectrodes, a researcher recorded nerve signals in four neurons in the brain . The neurons are called A, B, C, and D in the table below. A, B, and C all can transmit signals to D. In three experiments, the animal was stimulated in different ways. The number of nerve signals transmitted per second by each of the cells is recorded in the table. Write a short paragraph explaining the different results of the three experiment. 09
- Write a Worm neuronal function assay paragraph about a worm neuronal function and find an experiment that could test why the worm may have this worm neuronal function. Such as a worm spiraling. One robust assay of worm behavior is…. “Finish the sentence” and find an experiment that could determine why the worm behavior is this way.L-Dopa One of the first medications developed to treat Parkinson's disease is a substance called L-DOPA (or Levodopa). This medication can be taken to reduce the motor symptoms of Parkinson's. Unfortunately there is no way to reverse or stop the death of the dopamine producing neurons, but L-DOPA is one of a few treatments that can help manage the symptoms. Your task is to investigate what L-DOPA is and explain why taking L-DOPA might reduce the symptoms of the disease. Write at least one paragraph (5 sentences) to explain your findings in the box below. Use the rubric here to make sure you are explaining the situation thoroughly. This should be entirely in your own words. Do not use phrases from the internet if you do not know what they mean. Rubric (use to check your work) Has major the main points misconceptions not understand of this topic Shows a Understands Clearly does complete understanding How do Neurons 100 85 70 50 use neurotransmitters like dopamine? What do neurons do when…Researchers investigating the effect of exercise on cognitive functions conducted a con- trolled experiment in which rats were randomly assigned to sedentary (Sed), low-intensity exercise (Low-Ex), or high-intensity exercise (High-Ex) groups. During this exercise regi- ment, rats were also trained to navigate a specialized water maze, and their escape la tency, the time it took them to escape the maze, was recorded. The results of this experi- ment are depicted in the figure below. escape latency (sec) 100 80 60- 40- 20 0- day 10 day 11 Escape latencies during the training phase Based on the data above, day 12 (b) Identify the control group in the experiment. sed -- low-ex -- high-ex (a) Identify the dependent and independent variables in the experiment. day 13 Respond to each part in 3 to 4 complete sentences. (c) Compare the effects of low-intensity and high-intensity exercise on the rats' cognitive func- tion during the training period.
- In the discussion section the authors wrote “The prevailing hypothesis about the action of tACS is the alternating fields can increase or decrease the power of oscillatory rhythms in the brain, and in a frequency-dependent manner, through synchronizing and desynchronizing neuronal networks [17].” a. Is the hypothesis a null hypothesis or an alternative/alternative hypothesis? b. By what word or words do you know that your answer to the question is correct? c. Why did you choose this word or words as an answer to the question?Describe Piaget's theory of cognitive development ?Let’s examine a neural pathway that involved three (3) neurons in sequence: one propagates an action potential from threshold stimulus of receptor to spinal cord; second propagates action potential superiorly to brain stem; and third propagates action potential from brain stem to part of cerebral cortex involved in perceiving the stimulus. Which of the following is correct classification of these neurons: a. all three are presynaptic b. first is presynaptic, other two are postsynaptic c. first and second are presynaptic, third is postsynaptic d. first and second are presynaptic, second and third are postsynaptic e. all three are postsynaptic