Retrosynthetic Analysis Question Q1- In the box draw the two possible starting materials you could use to synthesize the following molecules using the reaction indicated. Nucleophilic Subsitution Reaction Nucleophilic Subsitution Reaction Nucleophilic Subsitution Reaction Nucleophilic Subsitution Reaction followed Acid Catalyzed Hydration of Alkyne Nucleophilic Subsitution Reaction followed by hydroboration Oxidation of Alkyne H

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The compound below can be prepared with an alkyl iodide and a suitable nucleophile. Identify the alkyl iodide and the nucleophile that you would use. For an anionic nucleophile, you do not need to draw the counterion. Alkyl iodide: OH Draw Your Solution Nucleophile: Draw Your Solution SUPPORT

Don't use hand raiting please

Part A Rank the species below in order of decreasing nucleophilicity in protic solvents Rank the species from most to least nucleophilic. To rank items as equivalent, overlap them. Most Submit The correct ranking cannot be determined. Previous Answers Request Answer CH3CO₂ CH3S HO H₂O Reset Help Least

2) Circle the nucleophilic center(s) or electrophilic center(s) in each of the following compounds/ions: Nucleophiles a) Electrophiles b) ملة nogom ) SH h) مه لم

Place molecules in order from least nucleophilic to most nucleophilic and reasoning

Question 13 of 30 View Policies Current Attempt in Progress Propose an efficient synthesis for the following transformation: The transformation above can be performed with some reagent or combination of the reagents listed below. reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is solution, provide just one answer. A C t-BUOK HBr, ROOR Na2Cr207, H2SO4, H2O NaOH F G H H2, Lindlar's cat. 1) O3; 2) DMS TSCI, py dilute H2SO4 K 1) LIAIH2; 2) H3O- DMP or PCC HBr 1) MeMgBr; 2) H3O* W SS N DELL

Cs Scanned with CamScanner 2. Show two reaction schemes to synthesize the following compounds. Pick one reaction scheme and draw the step-by-step reaction mechanism. а. HO-

Br CH3OH + Br-Br H3CO The mechanism proceeds through a first cationic intermediate, intermediate 1. Nucleophilic attack leads to intermediate 2, which goes on to form the final product. In cases that involve a negatively charged nucleophile, the attack of the nucleophile leads directly to the product. +Br + CH3OH Br Intermediate 1 Intermediate 2 (product) In a similar fashion, draw intermediate 1 and intermediate 2 (final product) for the following reaction. OH + Br2 + HBr Br racemic mixture • Pay attention to the reactants, they may differ from the examples. In some reactions, one part of the molecule acts as the nucleophile. • You do not have to consider stereochemistry. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate intermediate 1 and intermediate 2 using the → symbol from the dropdown menu.