Questions 1015MSC Chemistry of Biological Systems II 1. What is the purpose of the concentrated sulfuric acid in the preparation of aspirin? 2. Anhydride means "without water". Suppose 1 M H₂SO4 were substituted for the concentrated H₂SO4. Would the yield of acetylsalicylic acid be increased, decreased, or unaffected by the substitution? Explain.

Why are the interactions between H2O molecules stronger than those between HF molecules, even though the polarity of the HF bond is larger than the polarity of the OH bond?

4) Fill in the blanks for the following transformations. HI (concentrated) a) NaNH, b) Ph Br H* H₂ Lindlar catalyst Na*: CECH

Question 11 (Predict the Product): The following oxidation produces one product. H i) 1 eq NaBH4 EtOH ii) dil HCI Predict the product of this reaction. A) A is the product of this reaction B B is the product of this reaction C is the product of this reaction A OH or OH B H or OH C OH

9. Which of these compounds has chemical properties most similar to the chemical properties of ethanoic acid? 1. C₂H-COOH 2C₂H₂OH 3. C₂H5COOC₂H5 4. C₂H5OC₂H5

5. Synthesis of aspirin a. Write the sequence of reactions to produce aspirin using salicylic acid, acetic anhydrous, and phosphoric acid.

What is the product and what kind of reaction is this?

When setting up an organic reaction for the first time, a concentration of reactants in tens to hundreds of micromolar range (mM) is often required. How much solvent (DCM) is required to prepare a solution that has a reactant concentration of 200mM? a) 0.126mL b) 1.26mL c) 12.60mL d) 126mL e) None of the options is correct.

What are the products of the reaction of Pb(C2H3O2)2 aq with NACl aq