Questions 1. What was the effect of increasing extracellular K+ to 100 mM on the membrane's potential? 2. Explain why the above change occurred.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Question
**Resting Membrane Potential - Data**

| Concentration (mM) | K⁺ Inside | K⁺ Outside | Na⁺ Inside | Na⁺ Outside | Membrane Voltage (mV) |
|---------------------|-----------|------------|------------|-------------|-----------------------|
|                     | 140       | 4          | 10         | 140         | -68.036               |
|                     | 140       | 100        | 10         | 140         | -22.5                 |
|                     | 140       | 4          | 10         | 200         | -61.545               |

**Questions**

1. What was the effect of increasing extracellular K⁺ to 100 mM on the membrane's potential?

2. Explain why the above change occurred. 

**Explanation of Data**

This table represents the changes in membrane voltage (mV) with different ionic concentrations (in mM) inside and outside the cell. The first row is the baseline scenario, with typical K⁺ and Na⁺ distribution, showing a membrane voltage of -68.036 mV. The second row indicates an increase in extracellular K⁺ concentration to 100 mM, resulting in a membrane voltage shift to -22.5 mV. The third row examines an increase in extracellular Na⁺ to 200 mM, with the voltage changing to -61.545 mV.

Readers are encouraged to consider how these changes affect the resting membrane potential, reflecting on the Nernst equation and the principles of ionic equilibrium across a cell membrane.
Transcribed Image Text:**Resting Membrane Potential - Data** | Concentration (mM) | K⁺ Inside | K⁺ Outside | Na⁺ Inside | Na⁺ Outside | Membrane Voltage (mV) | |---------------------|-----------|------------|------------|-------------|-----------------------| | | 140 | 4 | 10 | 140 | -68.036 | | | 140 | 100 | 10 | 140 | -22.5 | | | 140 | 4 | 10 | 200 | -61.545 | **Questions** 1. What was the effect of increasing extracellular K⁺ to 100 mM on the membrane's potential? 2. Explain why the above change occurred. **Explanation of Data** This table represents the changes in membrane voltage (mV) with different ionic concentrations (in mM) inside and outside the cell. The first row is the baseline scenario, with typical K⁺ and Na⁺ distribution, showing a membrane voltage of -68.036 mV. The second row indicates an increase in extracellular K⁺ concentration to 100 mM, resulting in a membrane voltage shift to -22.5 mV. The third row examines an increase in extracellular Na⁺ to 200 mM, with the voltage changing to -61.545 mV. Readers are encouraged to consider how these changes affect the resting membrane potential, reflecting on the Nernst equation and the principles of ionic equilibrium across a cell membrane.
Expert Solution
steps

Step by step

Solved in 2 steps

Blurred answer
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Anatomy and Physiology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Anatomy & Physiology
Anatomy & Physiology
Anatomy and Physiology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Human Anatomy
Human Anatomy
Anatomy and Physiology
ISBN:
9780135168059
Author:
Marieb, Elaine Nicpon, Brady, Patricia, Mallatt, Jon
Publisher:
Pearson Education, Inc.,
Anatomy & Physiology: An Integrative Approach
Anatomy & Physiology: An Integrative Approach
Anatomy and Physiology
ISBN:
9780078024283
Author:
Michael McKinley Dr., Valerie O'Loughlin, Theresa Bidle
Publisher:
McGraw-Hill Education
Human Anatomy & Physiology (Marieb, Human Anatomy…
Human Anatomy & Physiology (Marieb, Human Anatomy…
Anatomy and Physiology
ISBN:
9780321927040
Author:
Elaine N. Marieb, Katja Hoehn
Publisher:
PEARSON