Previously harvested from other animals, which of the following human-derived, disorder-treating agents are mass produced thanks to genetic engineering? (Check all that apply) A.) Insulin B.) Growth Hormones C.) Clotting Factor D.) Dynein

Introduction: There’s quite a bit of interest around repurposing extant drugs to treat infections by targeting host pathways that pathogens rely on. Here are a few potential drugs: 1) A drug that inhibits endocytosis, but not phagocytosis. 2) A drug that inhibits degradation of cytoplasmic proteins into smaller peptides, preventing their cycling back into amino acids. 3) A drug used to treat porphyria that reduces the reactivity of heme. 4) A drug that depletes glutathione, a chemical which protects red blood cells against the reactivity of heme. 5) A drug that reduces expression of the ACE-2 protein.   Question: Pick a drug and an infection that the drug is likely to be good at treating, or pick an infection and a drug that would most likely make the infection substantially worse. Which drug and pathogen did you pick? Do you think it’ll make it better or worse?

1 Which of the following is a contraindication to the antiarrhythmic Amiodarone?  A) Tachycardia B) Allergy to Lidocaine C) Bradycardia D) Hypertension  2 Which of the following is a common side effect of cholesterol medication? A) Muscle pain B) Diabetes C) Headache D) Decreased urination  3 Which of the following most accurately describes the mechanism of action of a "statin"?  A) Inhibits platelet aggregation B) Inhibits sodium excretion in the kidneys C) Inhibits cholesterol production in the liver D) Inhibits sodium reabsorption in the loop of Henle 4 Which of the following is an indication to the antiarrhythmic Amiodarone?  A) Bradycardia B) Hypercalcemia C) Hypertension D) Supraventricular Tachycardia (SVT)

Which of the following is an enabling characteristic for cancer that can increase the likelihood of both passenger and driver mutations? a) Increased angiogenesis O b) Tumor-promoting inflammation O c) Avoiding immune destruction O d) Genome instability acer

4. A physician orders Humulin R 35 units qam and q5pm and Humulin N 60 units qam. a) How many 10-mL vials of Humulin R U-100 insulin are needed for a one month supply? b) How many 10-mL vials of Humulin N U-100 insulin are needed for a one month supply?

When a medical chart requires you to use "approved" drug names, to which of the following does it refer? A) IUPAC B) Generic C) Chemical D) Trade

In what ways may nanotechnology help in the fight against disease? What is a different sort of nanotechnology, and how does it function?

(a) Explain how polymorphism contributes to different drug metabolism among individuals. (b) What are the potential consequences of a poor metabolizer?

Which of the following best describes the mechanism of action of the antibiotic streptomycin? A. it disrupts protein synthesis in resistant bacteria. B. Streptomycin inhibits cell wall synthesis in all bacterial species. C. Streptomycin creates mutations in bacteria which cause them to become resistant. D. It disrupts protein synthesis in nonresistant bacteria.

Which antiretroviral drug class does Zidovudine (AZT) belong to? a) Non-nucleoside reverse transcriptase inhibitors (NNRTIs) b) Nucleoside reverse transcriptase inhibitors (NRTIs) c) Protease inhibitors d) Integrase inhibitors