Question 3. You have identified a mouse that develops dry skin due to increased evaporation. Which of the four junction that we discussed do you think may be dysfunctional in this mouse?

Question 9. When the rate of loss of actin subunits from the pointed end of an actin filament is balanced by the rate of their addition to the barbed end what is this state called?

Question 3. The Lyme disease spirochete, Borrelia burgdorferi, abundantly produces outer surface lipoprotein A (OspA) in the tick vector but downregulates OspA in mammals in order to evade the immune system and maintain its natural enzootic cycle. The protein BosR is thought to regulate OspA. Below is a protein gel from the spirocete in a tick on the left and from the spirocete in a mammal on the right. From this gel, how is BosR regulating the expression of OspA? Please explain your answer. KD 37 - 20- 20- 250- 75- 50- 37- 25- 20- 15- - FlaB - BosR - OspC - OspA Double-click to show white space

QUESTION 2 A loss of function of Apaf1, the human equivalent of ced-4 in C. elegans, is most likely to result in which of the following? activation of a developmental pathway found in C. elegans but not in humans a form of cancer in which normal apoptosis fails excess activation of the human version of the ced-3 protease O extensive tissue damage due to excess apoptosis