Question 10 What can be said of two genes on the same chromosome, 49 map units apart? they are unlinked they are epistatic they are pleiotropic they are physically linked they are genetically linked

In Meselson and Radding modified Holliday model, following branch migration, what are the possible number of heteroduplex regions that can occur? 3 4

You are interested in studying position effect variegation in Drosophila using the chromosome depicted below: Deactivation of the w+ gene gives a white eye phenotype and deactivation of the rst+ gene gives a rough eye phenotype; the normal phenotypes are red and smooth. Because the rst+ and w+ genes have now been placed close to a heterochromatic domain, some sections (or sectors) of the eye display mutant phenotypes due to gene deactivation while others display the normal, wild type phenotype. Which phenotype would you not expect to see rst w Inverted X chromosome white smooth eye sectors white rough eye sectors red smooth eye sectors red rough eye sectors

The homologous chromosome pairs in our cells do not carry identical sequences in all loci. This heterozygosity (difference between the two.copies) can be altered in cancer: in fact, loss of heterozygosity at many loci is observed in cancer cells, through an increase in either homozygosity (two identical copies) or hemizygosity (i.e. loss of one copy). Researchers can take advantage of this loss of heterozygosity in cancer cells to identify genomic loci that contain cancer-critical genes. What type of gene would you expect to find in chromosomal regions with a loss of heterozygosity? Proto-oncogenes or tumour suppressor genes? Choose the correct answer here Proto-oncogenes Tumour Suppressor genes

A group of scientists sequenced the genomes of 12 species of Drosophila (Drosophila 12 Genomes Consortium. 2007. Nature 450:203–218). Data on genome sizes and numbers of protein-encoding genes from this study are given in the accompanying table. Plot the number of protein-encoding genes as a function of genome size for the 12 species of Drosophila. Is there a relation between genome size and number of genes in fruit flies? How does this compare with the relation between genome size and number of genes across all eukaryotes?

Examine Figure . What type of chromosome (metacentric, submetacentric, acrocentric, or telocentric) is chromosome 1? What about chromosome 4?

What are the factor of expressed sequence tag?

A line of mouse cells is grown for many generations in a medium with 15N. Cells in G1 are then switched to a new medium that contains 14N. Draw a pair of homologous chromosomes from these cells at the following stages, showing the two strands of DNA molecules found in the chromosomes. Use different colors to represent strands with 14N and 15N. Q. Cells in G1, before switching to medium with 14N

Internal Structures Function/significance Atrium (right & left) (plural – Atria)       Bicuspid valve (AKA Mitral Valve)       Chordae tendinae       Endocardium       Interventricular septum       Myocardium         Papillary muscle         Semilunar valves (Aortic and Pulmonary)         Trabeculae carnae         Tricuspid valve       Ventricle (right and left)

6). To investigate the genetic control of locomotive behavior in the diploid nematode, Caenorhabditis elegans, eight "wiggly" mutants were isolated, which wiggle in an uncoordinated way rather than smoothly gliding. These eight mutants were crossed together in all possible pairwise combinations, yielding the results summarized in the table above (+ means that all the progeny were wild type, and m means that all the progeny showed the wiggly mutant phenotype). Organize the eight mutations into con lementation groups, each consisting of a group of mutations affecting the same gene. 1 2 3 4 5 6 7 8 1 E N+E 2 3+1 m + m 4 5 + m m E+ + + EE 6 ++E E+ +EE m m + + + + + + + + + m 7 8 ++4 ∞+E +E m m ++ E