Protein structure is determined solely by a protein’s amino acid sequence. Should a genetically engineered protein in which the original order of all amino acids is reversed have the same structure as the original protein?

Can the tertiary structure of a protein depend on the type of cell system used for synthesis? Explain.

Consider the 20 standard amino acids and their structures. Choose a set of 6 amino acids that you think could theoretically be eliminated from existence and still allow proteins to fold, function, and support life with the remaining 14. Eliminating amino acids from existence would result in a need for changes to the amino acid sequence of proteins, however your choices of amino acids to eliminate should result in minimal changes to the way proteins are currently structured and function. For each amino acid that you propose to eliminate defend your choice with a 2-3 point explanation using reasoning. Your answer should be no longer than 1.5 pages in length and you should start a new paragraph for each amino acid that you select to be eliminated.

Within a naturally-occurring polypeptide, under neutral pH conditions (pH = 7.0), which of the following amino acids always has a negatively charged carboxyl group? the first amino acid in the primary structure histidine lysine arginine the last amino acid in the primary structure

Can a mutation change a protein’s tertiary structure without changing its primary structure? Explain your answer.

Why is having flexible and unstructured regions of a protein important for the function of the protein?

When an inappropriate amino acid is substituted in place of another, as occurs in certain genetic disorders, the resulting protein is either poorly functional or non-functional. Since proteins contain hundreds if not thousands of amino acids, why should the change of a single amino acid be so critical?

Which type of amino acid would you expect to find in large numbers in a protein found in a deep-sea hydrothermal vent (a very hot environment)? A.)Polar amino acids B.)Cysteines C.)Hydrophobic amino acids D.)Nonpolar amino acids

Can a mutation change a protein’s primary structure without changing its secondary structure? Explain your answer.

Describe three major functions of proteins in the human body with one example for each.