Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Protein phosphorylation is commonly involved with all of the
following except
(A) activation of receptor tyrosine kinases.
(B) activation of protein kinase molecules.
(C) activation of G protein-coupled receptors.
(D) regulation of transcription by signaling molecules.
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution
Trending nowThis is a popular solution!
Step by stepSolved in 3 steps
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- (i) For non-lipid soluble signalling molecules, which class of receptors are required? Please give two examples of non-lipid signalling molecules and explain how these signalling molecules induce intracellular signalling to change the cell behaviour. (ii) Compare and contrast beta catenin and p53 signalling, and explain their functions in the nucleus.arrow_forwardWhen a chemical signal binds to an intracellular receptor ... a) ... it leads to the activation of G proteins. b) ... causes the receptor-hormone complex to open or close ion channels. c) ... the cell reacts faster than when a chemical signal binds to membrane-bound receptors. d) ... it leads to the formation of mRNA. e) ... the chemical signal is usually a large, water-soluble molecule.arrow_forwardDiagram and describe the four types of regulatory mechanisms of the cyclin-dependent kinases (Cdks)arrow_forward
- 21. Given the generic signaling pathway in the figure below, find out which label is incorrect. A) 1. Ligand B) 2. Receptor protein C) 3. Transcription factors D) 4. Effector proteins Answer: Explanation: * metabolic enzyme cytoskeletal protein cellular changes 1 2 3 transcriptional regulatorarrow_forwardJhat are the two problems that a protein component of an intracellular signaling circuit must solve?arrow_forwardCyclin-dependent kinases are a type of "microchip" protein that require multiple inputs (i.e., structural alterations) to be activated-- and thus are active only under specific conditions (as shown in the diagram below). How does limiting activity to when all conditions have been met help the cell function properly? INPUTS has this phosphate been removed? been added? has this is cyclin present? phosphatearrow_forward
- Nerve growth factor binds to which type of receptor? a.) Receptor tyrosine phosphatases b.) Receptor Serine/Threonine Kinase c.) Receptor guanylyl cyclase d.) Receptor tyrosine kinasearrow_forwardWhat is the difference between a protein kinase and a secondmessenger? Can both operate in the same signal transduction pathway?arrow_forwardIf you have a protein kinase that is regulated by both small molecule inhibitors as well as by phosphorylation, and is part of a cooperative enzyme complex that works as part of a larger pathway involving kinase and GTPase proteins please explain where on this protein regulation could occur, how different types of inhibition could control the function of the protein as well as the function of the complex, and how the protein could regulate other proteins. (This question was previously answered but it was answered incompletely mentioning an herbicide developed in the 1950's. Apparently, it was a plagiarized excerpt from an NCBI article. This is a repost for a full and complete answer. Thank you so much for your help! :) )arrow_forward
- Signaling activity of G proteins is controlled by GTPase activating proteins (GAPs) and Guanine exchange factors (GEFs). What are the mechanisms by which GAPS and GEFs control G protein functions? GEFS inhibit G protein functions by stimulating GTP hydrolysis; GAPs activate G protein functions by stimulating GDP-GTP exchange. O GAPS inhibit G protein functions by stimulating GTP hydrolysis; GEFs activate G protein functions by stimulating GDP-GTP exchange. GEFS inhibit G protein functions by stimulating GTP hydrolysis; GAPS activate G protein functions by inhibiting GDP-GTP exchange. GAPs stimulate G protein functions by blocking GTP hydrolysis; GEFS inhibit G protein functions by stimulating GTP-GDP exchange. GAPS inhibit G protein functions by stimulating GDP-GTP exchange; GEFS activate G protein functions by stimulating GTP hydrolysisarrow_forwardBriefly explain in your words the role of how Inside-out signaling of integrin occurs?arrow_forwardYou stimulated the cell with a ligand and analyzed the response. Upon ligand treatment, the cell increased the expression of gene α and decreased expression of gene β. When you inhibit cyclic AMP production by treating the cell with an inhibitor of Adenylyl cyclase, the increased expression of gene α was not observed but the decrease gene β expression was still observed. a) What you can expect for gene α regulation by this ligand? What signaling mechanism could be used? b) To determine how gene β is regulated by the ligand via what signaling mechanism, provide your hypothesis and indicate a potential experiment that you can perform to test that.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education