Propose a sequence of reactions to synthesize the target compound below from the indicated starting material. You may use any other organic and/or inorganic reagents necessary to complete your synthesis, but all carbon atoms in the target must be derived from the starting material specified. It is only necessary to give overall transformations in answering this question. Please DO NOT provide curved arrow mechanjsms for the reactions that you use. OH Prepare from as the source of all C atoms in the target Acetophenone (TARGET) 2-Phenylethanol (STARTING MATERIAL)

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**Title: Organic Synthesis Challenge: Acetophenone from 2-Phenylethanol**

**Objective:**
Propose a sequence of reactions to synthesize the target compound, acetophenone, from the indicated starting material, 2-phenylethanol.

**Instructions:**
- You may use any other organic and/or inorganic reagents necessary to complete your synthesis.
- All carbon atoms in the target must be derived from the specified starting material.
- It is only necessary to provide overall transformations in this question.
- Please DO NOT provide curved arrow mechanisms for the reactions you use.

**Chemical Structures:**
- **Acetophenone (TARGET):** The structure shows a benzene ring attached to a carbonyl group (C=O) linked to a methyl group (CH₃).
  
- **2-Phenylethanol (STARTING MATERIAL):** This structure consists of a benzene ring connected to an ethyl chain terminating with a hydroxyl group (OH).

**Guidelines:**
Using 2-phenylethanol as the source of all carbon atoms, synthesize acetophenone by proposing appropriate chemical transformations.

**Note:** This activity enhances understanding of reaction pathways and the utilization of functional groups in organic synthesis.
Transcribed Image Text:**Title: Organic Synthesis Challenge: Acetophenone from 2-Phenylethanol** **Objective:** Propose a sequence of reactions to synthesize the target compound, acetophenone, from the indicated starting material, 2-phenylethanol. **Instructions:** - You may use any other organic and/or inorganic reagents necessary to complete your synthesis. - All carbon atoms in the target must be derived from the specified starting material. - It is only necessary to provide overall transformations in this question. - Please DO NOT provide curved arrow mechanisms for the reactions you use. **Chemical Structures:** - **Acetophenone (TARGET):** The structure shows a benzene ring attached to a carbonyl group (C=O) linked to a methyl group (CH₃). - **2-Phenylethanol (STARTING MATERIAL):** This structure consists of a benzene ring connected to an ethyl chain terminating with a hydroxyl group (OH). **Guidelines:** Using 2-phenylethanol as the source of all carbon atoms, synthesize acetophenone by proposing appropriate chemical transformations. **Note:** This activity enhances understanding of reaction pathways and the utilization of functional groups in organic synthesis.
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