Problem Set 1 7. (Chapter 8) Inversions are known to affect crossing-over. The following homologs have the indicated gene order (the circles are the centromeres) A B CD E F A D C B E F a. Considering the position of the centromere, what is this sort of inversion called? b. Diagram the alignment of these chromosomes at the end of Prophase I of Meiosis (which is after they have replicated in S phase of Interphase, i.e.. there should be four sister chromatids in your diagram) [See Figure 8.11]. c. Draw the results of a single crossover between homologous genes C and D in the inversion at the end of Meiosis (i.e., draw what the four daughter chromosome products would look like) indicating whether they would be viable (no duplications or deletions and monocentric) or inviable (with duplications and/or deletions), and acentric (no centromere), monocentric (one centromere) or dicentric (two centromeres).

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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Problem Set 1
7. (Chapter 8) Inversions are known to affect crossing-over. The following homologs have the
indicated gene order (the circles are the centromeres);
A
B
C
D
E
F
A D C
BE F
a. Considering the position of the centromere, what is this sort of inversion called?
b. Diagram the alignment of these chromosomes at the end of Prophase I of Meiosis (which is
after they have replicated in S phase of Interphase, i.e., there should be four sister chromatids in
your diagram) [See Figure 8.11].
c. Draw the results of a single crossover between homologous genes C and D in the inversion at
the end of Meiosis (i.e., draw what the four daughter chromosome products would look like)
indicating whether they would be viable (no duplications or deletions and monocentric) or
inviable (with duplications and/or deletions), and acentric (no centromere), monocentric (one
centromere) or dicentric (two centromeres).
Transcribed Image Text:Problem Set 1 7. (Chapter 8) Inversions are known to affect crossing-over. The following homologs have the indicated gene order (the circles are the centromeres); A B C D E F A D C BE F a. Considering the position of the centromere, what is this sort of inversion called? b. Diagram the alignment of these chromosomes at the end of Prophase I of Meiosis (which is after they have replicated in S phase of Interphase, i.e., there should be four sister chromatids in your diagram) [See Figure 8.11]. c. Draw the results of a single crossover between homologous genes C and D in the inversion at the end of Meiosis (i.e., draw what the four daughter chromosome products would look like) indicating whether they would be viable (no duplications or deletions and monocentric) or inviable (with duplications and/or deletions), and acentric (no centromere), monocentric (one centromere) or dicentric (two centromeres).
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