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Please give clinical situations in which you would use isotonic, hypotonic, and hypertonic solutions? Please be sure to explain your answers.
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- Choose the one answer that fits best. Which of the following statements regarding the proper procedure for using Micropipettes is NOT correct? O a. You cannot use a 2-20 µl micropipette to pipet 200 µl O b. To expel all the liquid from the tip, you have to press the eject button O c. To draw up solution, press and hold the plunger at the first stop before entering the solution O d. Micropipettes always require the use of a disposable plastic tip O e. While pipetting, micropipettes should always be held as straight as possibleGive detailed Solution (Don't give Handwritten answer)Match the following descriptions to the tonicity adjusting method which they describe. - Cryoscopic method - White-Vincent Method - E method - Sprowl's method It is the most widely used method in adjusting tonicity by the amount of sodium chloride. This method expresses the freezing point in terms of 1% solution. This method uses a constant that denotes the volume of isotonic preparation in milliliters when 1 gram of sodium chloride is dissolved in water. This method uses a constant of 0.3 to denote the weight of the drug. This method uses the equation "V = 33.33E".
- Patch clamp What is patch clamp technique? Identify two features of the patch clamp technique that make it a useful tool in studying cellular electrophysiology. Explain each thoroughly. What is the role of the reference electrode in the patch clamp technique? Discuss how it works.Give Detailed Solution with explanation(don't give Handwritten answer)Give detailed Solution with explanation needed(don't give Handwritten answer)
- A pharmacist prepares 80 mL of an isotonic solution of 1.1 %w/v Lidocaine HCl (E-value 0.2). To prepare the solution, he dissolves Lidocaine HCl in purified water to make an isotonic solution. Then he dilutes the Lidocaine HCl solution with 0.9%w/v sterile sodium chloride to complete the formulation. How many milliliters of purified water is needed to make the formulation by this method?Give explanation of correct option and explanation of incorrect options. Hand written solutions are strictly prohibited.Give detailed Solution with explanation (don't give Handwritten answer, )
- By applying Gravimetry, Titration (Chemical indicator) and Potentiometry lessons which technique should be used in following situations. Explain your answer. In your explanation, state what is the advantage of the technique you chose over other technique and /or the barrier/difficulty of using the technique. Your choice should not be dependent on cost. For chem students- Total Acid content per tablet of a newly developed drug that has yellow coating Target level is 1%.Please help, will provide helpful for correct solution.Discuss in chemical detail the mechanism of action (how it works) of IMAC. Compare and contrast gel filtration chromotography with IMAC. Discuss the pros and cons for each technique. Why would a scientist prefer one technique over another? In what situations would one technique be more viable than the other?