One way that regulation is often studied is by examining the effects of mute ons. For example, mutations within the parts of the lac operon have been well studied. Which of these mutants would be considered a constitutive mutant (the operon is always on)? a mutation in CAP that prevents the binding of CAMP a mutation in one of the structural genes that prevents the transport of lactose into the cell a mutation that disables the promoter for the operon a mutation that disables the repressor

Biochemistry
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Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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**Understanding the Effects of Mutations in Gene Regulation**

One common method to study regulation is by examining the effects of mutations. In particular, mutations within the parts of the *lac* operon have been extensively researched. Consider the following scenario to determine which of these mutations would be classified as a constitutive mutant, meaning the operon is always active:

- ○ A mutation in CAP that prevents the binding of cAMP.
- ○ A mutation in one of the structural genes that prevents the transport of lactose into the cell.
- ○ A mutation that disables the promoter for the operon.
- ○ A mutation that disables the repressor.

In genetic studies, understanding mutations and their consequences plays a crucial role in comprehending gene regulation and expression.
Transcribed Image Text:**Understanding the Effects of Mutations in Gene Regulation** One common method to study regulation is by examining the effects of mutations. In particular, mutations within the parts of the *lac* operon have been extensively researched. Consider the following scenario to determine which of these mutations would be classified as a constitutive mutant, meaning the operon is always active: - ○ A mutation in CAP that prevents the binding of cAMP. - ○ A mutation in one of the structural genes that prevents the transport of lactose into the cell. - ○ A mutation that disables the promoter for the operon. - ○ A mutation that disables the repressor. In genetic studies, understanding mutations and their consequences plays a crucial role in comprehending gene regulation and expression.
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