OEt 1) Na OEZ OEt 2) H30t G Ro- 1) KOEBU RO 2.) Hgut

Identify the nucleophile that attacks the carbocation intermediate in the acid catalyzed hydration is shown A. HO- B. H2O C. H+ D. H3O+

Why does this reaction not undergo SN2 ?

Among a primary, secondary, or tertiary carbocation, which is most favored for SN1 reactions? Explain why

For the following reactions, determine which mechanism they will follow, explain why the substitution of the alkyl halide doesn't affect the mechanism in an elimination reaction a. draw the mechanism showing regiochemistry of both possible products b. determine which product would be the most stable and therefore the major product c. Draw reaction coordinate diagrams and write rate laws for each reaction mechanism you Br yo you HO

For the third step of the first reaction why is there a ch2-ch3 group connected to the epoxide, shouldn't there just be a ch3 group connected to it?

Add the missing nucleophile to the substitution reaction in the drawing area below. Note for advanced students: You can assume the correct solvent conditions are used in this reaction. ö 80 Ar

what is the Nature of the leaving group (LG)? 5. what is the relative size of activation energy (Ea) for each reaction? 6. what is the Hammond's postulate? 7. what are the Relative thermodynamic stability of the reactive intermediates? 8. what is Influence of the solvent (if given) on the reactions and intermediates?

1. Provide the mechanism of the reaction shown in the picture. 2. Explain why it cannot be done in basic conditions. 3. Why is the enol tautomer favored over the keto tautomer?

1. Of the two unimolecular reactions shown, decide which you think would be faster, i.e., which would have a higher relative rate constant (krel)? 2. Based on your answer, draw two lines on one reaction coordinate diagram that show the relative progress of each reaction along its path to product indicated? 3. what is Bond dissociation energy of the C-LG bond? 4. what is the Nature of the leaving group (LG)? 5. what is the relative size of activation energy (Ea) for each reaction? 6. what is the Hammond's postulate? 7. what are the Relative thermodynamic stability of the reactive intermediates? 8. what is Influence of the solvent (if given) on the reactions and intermediates?