O Macmillan L Consider the isomers of tert-butylcyclohexanol in conformational structures. Two are cis-2-tert-butylcyclohexanol and two are cis-3-tert-butylcyclohexanol. Indicate which is the more stable conformation for each pair, and indicate which of all four conformations is the most stable. S OH A Select the more stable conformation of cis-2-tert-butylcyclohexanol. 0000 D C A | | B B OH HO C [C Select the more stable conformation of cis-3-tert-butylcyclohexanol. | ID ปี ОН A D

3-44 Draw the two chair conformations of each compound and label the substituents as axial and equatorial. In each case, deter- mine which conformation is more stable. (a) cis-1-ethyl-2-isopropylcyclohexane (c) cis-1-ethyl-3-methylcyclohexane (e) cis-1-ethyl-4-methylcyclohexane (d) (b) trans-1-ethyl-2-isopropylcyclohexane trans-1-ethyl-3-methylcyclohexane trans-1-ethyl-4-methylcyclohexane (f)

Question 3 of 7 > O Macmillan Learning For the substituted cyclohexane compound shown, identify the atoms that are cis to the hydroxyl (OH) substituent. Br H D CI F C A C E ECH 3 H I HO GF BH Identify the atoms that are cis to the hydroxyl. G K A F H CI K HJ HI B D H J

Draw a perspective representation of the most stable conformation of 3-methylhexane. Draw the molecule on the canvas by choosing buttons from the Tools (for bonds and charges), Atoms, and Templates toolbars. 0 + 7 C Akri C H 12D EXP CONT Marvin JS by ChemAxon 1 H CI P UNOS J

Identify the most stable chair conformation of the most stable isomer of 1-ethyl-3-isopropylcyclohexane. 01 O HII ON OV III IV

Question 6 of 7 The images illustrate isomers of 1,2-di(2-methylpropyl)cyclohexane in conformational structures. Two are cis and two are trans. Indicate which is the more stable conformation for the cis and which for the trans, and indicate which of all the conformations is the most stable. O Macmillan Learning H H H H H # -H H H H A H H A B D H Н H H H H B H THE THE D H H For each question, if both conformations of the isomer are equally stable, select both. Select the more stable conformation of cis-1,2-di(2-methylpropyl)cyclohexan

Please don't provide handwriting solution

4 Practice 2 3-9 4.8 Conformational Analysis of Butane The graph below represents the relative energies of the conformations of butane: ww B Relative energy -1- —— 0° 60° 120° 180° 240° 300° 360° Angle of rotation Select the Newman projection that corresponds with position C on the graph (an angle of rotation of 120 degrees). HA 3 H I I I I # CH3 CH 3 CH 3 CH3 -I H HH CH3 CH3 CH3 80⁰0 CH3 H I I Н 4 000 000 % 6 MacBook Air 7 8 DIL FB 9 0

Q 7 please