Motor neuron 1. 4 Muscle fiber nucleus Myofibril of muscle fiber Figure 10.15. Details of the neuromuscular junction. O bluedoor, LLC The numbers 1-4 indicate the chain of events that occur at the neuromuscular junction. Put these events in chronological order by placing a 1 in the blank before the first event, etc. Refer back to Figure 10.15 for information. Acetylcholine diffuses across the synaptic cleft. Nerve impulse reaches the axon terminal. Synaptic vesicles release acetylcholine into the synaptic cleft. Acetylcholine binds to receptors at the motor end plate. Answer the following questions. 1. Which event listed above is the point at which myasthenia gravis interrupts the process? Explain why. 2. One treatment for myasthenia gravis is a medication that blocks the activity of acetylcholinesterase. Suggest why this might be a successful treatment.

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Motor neuron
1.
4
Muscle fiber
nucleus
Myofibril of
muscle fiber
Figure 10.15. Details of the neuromuscular junction.
O bluedoor, LLC
Transcribed Image Text:Motor neuron 1. 4 Muscle fiber nucleus Myofibril of muscle fiber Figure 10.15. Details of the neuromuscular junction. O bluedoor, LLC
The numbers 1-4 indicate the chain of events that occur at the neuromuscular junction. Put these
events in chronological order by placing a 1 in the blank before the first event, etc. Refer back to
Figure 10.15 for information.
Acetylcholine diffuses across the synaptic cleft.
Nerve impulse reaches the axon terminal.
Synaptic vesicles release acetylcholine into the synaptic cleft.
Acetylcholine binds to receptors at the motor end plate.
Answer the following questions.
1. Which event listed above is the point at which myasthenia gravis interrupts the process?
Explain why.
2. One treatment for myasthenia gravis is a medication that blocks the activity of
acetylcholinesterase. Suggest why this might be a successful treatment.
Transcribed Image Text:The numbers 1-4 indicate the chain of events that occur at the neuromuscular junction. Put these events in chronological order by placing a 1 in the blank before the first event, etc. Refer back to Figure 10.15 for information. Acetylcholine diffuses across the synaptic cleft. Nerve impulse reaches the axon terminal. Synaptic vesicles release acetylcholine into the synaptic cleft. Acetylcholine binds to receptors at the motor end plate. Answer the following questions. 1. Which event listed above is the point at which myasthenia gravis interrupts the process? Explain why. 2. One treatment for myasthenia gravis is a medication that blocks the activity of acetylcholinesterase. Suggest why this might be a successful treatment.
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