Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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percentage purity of an ibuprofen sample was determined by a reversed phase HPLC
method as follows:
Y
Der
●
A calibration curve of peak area versus concentration (ug/mL) of pure ibuprofen was
constructed
The ibuprofen sample for analysis was prepared by taking 10.0204 g of powder and
dissolving it in/1Lbf distilled water (solution A). 1 ml of the latter solution was
further diluted to IL with distilled water (solution B). Solution B was analysed by
HPLC analysis
Results
The equation for the best-fit line of the calibration curve is:
y=26820x-1323.8.
●
The average peak area for the ibuprofen sample (solution B) was 266796.2
Calculate the percentage purity of the ibuprofen powder.
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Transcribed Image Text:percentage purity of an ibuprofen sample was determined by a reversed phase HPLC method as follows: Y Der ● A calibration curve of peak area versus concentration (ug/mL) of pure ibuprofen was constructed The ibuprofen sample for analysis was prepared by taking 10.0204 g of powder and dissolving it in/1Lbf distilled water (solution A). 1 ml of the latter solution was further diluted to IL with distilled water (solution B). Solution B was analysed by HPLC analysis Results The equation for the best-fit line of the calibration curve is: y=26820x-1323.8. ● The average peak area for the ibuprofen sample (solution B) was 266796.2 Calculate the percentage purity of the ibuprofen powder.
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